Earp JC - Search Results

1

Modeling effects of dexamethasone on disease progression of bone mineral density in collagen-induced arthritic rats.

Lon HK, DuBois DC, Earp JC, Almon RR, Jusko WJ. Lon HK, et al. Among authors: earp jc. Pharmacol Res Perspect. 2015 Oct;3(5):e00169. doi: 10.1002/prp2.169. Epub 2015 Aug 3. Pharmacol Res Perspect. 2015. PMID: 26516581 Free PMC article.

2

Assessment of drug interactions relevant to pharmacodynamic indirect response models.

Earp J, Krzyzanski W, Chakraborty A, Zamacona MK, Jusko WJ. Earp J, et al. J Pharmacokinet Pharmacodyn. 2004 Oct;31(5):345-80. doi: 10.1007/s10928-004-8319-4. J Pharmacokinet Pharmacodyn. 2004. PMID: 15669772

3

Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling.

Wetzler M, Earp JC, Brady MT, Keng MK, Jusko WJ. Wetzler M, et al. Among authors: earp jc. Clin Cancer Res. 2007 Apr 1;13(7):2261-70. doi: 10.1158/1078-0432.CCR-06-2468. Clin Cancer Res. 2007. PMID: 17404111 Free PMC article.

4

Modeling corticosteroid effects in a rat model of rheumatoid arthritis II: mechanistic pharmacodynamic model for dexamethasone effects in Lewis rats with collagen-induced arthritis.

Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Almon RR, Jusko WJ. Earp JC, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):546-54. doi: 10.1124/jpet.108.137414. Epub 2008 Apr 30. J Pharmacol Exp Ther. 2008. PMID: 18448864 Free PMC article.

5

Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats.

Earp JC, Dubois DC, Molano DS, Pyszczynski NA, Keller CE, Almon RR, Jusko WJ. Earp JC, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):532-45. doi: 10.1124/jpet.108.137372. Epub 2008 Apr 30. J Pharmacol Exp Ther. 2008. PMID: 18448865 Free PMC article.

6

Pharmacokinetics of dexamethasone in a rat model of rheumatoid arthritis.

Earp JC, Pyszczynski NA, Molano DS, Jusko WJ. Earp JC, et al. Biopharm Drug Dispos. 2008 Sep;29(6):366-72. doi: 10.1002/bdd.626. Biopharm Drug Dispos. 2008. PMID: 18613033 Free PMC article.

7

Quantitative dynamic models of arthritis progression in the rat.

Earp JC, Dubois DC, Almon RR, Jusko WJ. Earp JC, et al. Pharm Res. 2009 Jan;26(1):196-203. doi: 10.1007/s11095-008-9711-3. Epub 2008 Aug 30. Pharm Res. 2009. PMID: 18758921 Free PMC article.

8

Down-regulation of heat shock protein 70 improves arsenic trioxide and 17-DMAG effects on constitutive signal transducer and activator of transcription 3 activity.

Ghoshal S, Rao I, Earp JC, Jusko WJ, Wetzler M. Ghoshal S, et al. Among authors: earp jc. Cancer Chemother Pharmacol. 2010 Sep;66(4):681-9. doi: 10.1007/s00280-009-1210-7. Epub 2009 Dec 25. Cancer Chemother Pharmacol. 2010. PMID: 20035426 Free PMC article.

9

Utility of population pharmacokinetic modeling in the assessment of therapeutic protein-drug interactions.

Chow AT, Earp JC, Gupta M, Hanley W, Hu C, Wang DD, Zajic S, Zhu M; Population PK TPDI Working Group. Chow AT, et al. Among authors: earp jc. J Clin Pharmacol. 2014 May;54(5):593-601. doi: 10.1002/jcph.240. Epub 2013 Dec 6. J Clin Pharmacol. 2014. PMID: 24272952

10

The Utility of a Population Approach in Drug-Drug Interaction Assessments: A Simulation Evaluation.

Wang DD, Yu Y, Kassir N, Zhu M, Hanley WD, Earp JC, Chow AT, Gupta M, Hu C. Wang DD, et al. Among authors: earp jc. J Clin Pharmacol. 2017 Oct;57(10):1268-1278. doi: 10.1002/jcph.921. Epub 2017 May 17. J Clin Pharmacol. 2017. PMID: 28513856

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