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Page 1
Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships.
Wenzel SC, Hoffmann H, Zhang J, Debussche L, Haag-Richter S, Kurz M, Nardi F, Lukat P, Kochems I, Tietgen H, Schummer D, Nicolas JP, Calvet L, Czepczor V, Vrignaud P, Mühlenweg A, Pelzer S, Müller R, Brönstrup M. Wenzel SC, et al. Among authors: lukat p. Angew Chem Int Ed Engl. 2015 Dec 14;54(51):15560-4. doi: 10.1002/anie.201508277. Epub 2015 Oct 30. Angew Chem Int Ed Engl. 2015. PMID: 26514647
Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins.
Kling A, Lukat P, Almeida DV, Bauer A, Fontaine E, Sordello S, Zaburannyi N, Herrmann J, Wenzel SC, König C, Ammerman NC, Barrio MB, Borchers K, Bordon-Pallier F, Brönstrup M, Courtemanche G, Gerlitz M, Geslin M, Hammann P, Heinz DW, Hoffmann H, Klieber S, Kohlmann M, Kurz M, Lair C, Matter H, Nuermberger E, Tyagi S, Fraisse L, Grosset JH, Lagrange S, Müller R. Kling A, et al. Among authors: lukat p. Science. 2015 Jun 5;348(6239):1106-12. doi: 10.1126/science.aaa4690. Science. 2015. PMID: 26045430
Protein-Templated Hit Identification through an Ugi Four-Component Reaction*.
Mancini F, Unver MY, Elgaher WAM, Jumde VR, Alhayek A, Lukat P, Herrmann J, Witte MD, Köck M, Blankenfeldt W, Müller R, Hirsch AKH. Mancini F, et al. Among authors: lukat p. Chemistry. 2020 Nov 17;26(64):14585-14593. doi: 10.1002/chem.202002250. Epub 2020 Sep 30. Chemistry. 2020. PMID: 32428268 Free PMC article.
Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Schotte C, Lukat P, Deuschmann A, Blankenfeldt W, Cox RJ. Schotte C, et al. Among authors: lukat p. Angew Chem Int Ed Engl. 2021 Sep 6;60(37):20308-20312. doi: 10.1002/anie.202106718. Epub 2021 Aug 11. Angew Chem Int Ed Engl. 2021. PMID: 34180566 Free PMC article.
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens.
Fenwick MK, Pierce PG, Abendroth J, Barrett KF, Barrett LK, Bowatte K, Choi R, Chun I, Conrady DG, Craig JK, Dranow DM, Hammerson B, Higgins T, Lorimer DD, Lukat P, Mayclin SJ, Hewitt SN, Peng YP, Shanbhogue A, Smutney H, Stigliano MZZ, Tillery LM, Udell HS, Wallace EG, DeRocher AE, Phan IQ, Staker BL, Subramanian S, Van Voorhis WC, Blankenfeldt W, Müller R, Edwards TE, Myler PJ. Fenwick MK, et al. Among authors: lukat p. Commun Biol. 2024 Dec 5;7(1):1622. doi: 10.1038/s42003-024-07175-5. Commun Biol. 2024. PMID: 39639052 Free PMC article.
18 results