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Page 1
A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.
d'Avenia M, Citro R, De Marco M, Veronese A, Rosati A, Visone R, Leptidis S, Philippen L, Vitale G, Cavallo A, Silverio A, Prota C, Gravina P, De Cola A, Carletti E, Coppola G, Gallo S, Provenza G, Bossone E, Piscione F, Hahne M, De Windt LJ, Turco MC, De Laurenzi V. d'Avenia M, et al. Among authors: leptidis s. Cell Death Dis. 2015 Oct 29;6(10):e1948. doi: 10.1038/cddis.2015.280. Cell Death Dis. 2015. PMID: 26512958 Free PMC article.
MicroRNA regulation in cardiovascular disease.
da Costa Martins PA, Leptidis S, Salic K, De Windt LJ. da Costa Martins PA, et al. Among authors: leptidis s. Curr Drug Targets. 2010 Aug;11(8):900-6. doi: 10.2174/138945010791591322. Curr Drug Targets. 2010. PMID: 20415652 Review.
Nuclear calcium transients: Hermes Propylaios in the heart.
da Costa Martins PA, Leptidis S, De Windt LJ. da Costa Martins PA, et al. Among authors: leptidis s. Circulation. 2014 Jul 15;130(3):221-3. doi: 10.1161/CIRCULATIONAHA.114.010675. Epub 2014 Jun 13. Circulation. 2014. PMID: 24928679 No abstract available.
A deep sequencing approach to uncover the miRNOME in the human heart.
Leptidis S, El Azzouzi H, Lok SI, de Weger R, Olieslagers S, Kisters N, Silva GJ, Heymans S, Cuppen E, Berezikov E, De Windt LJ, da Costa Martins P. Leptidis S, et al. PLoS One. 2013;8(2):e57800. doi: 10.1371/journal.pone.0057800. Epub 2013 Feb 27. PLoS One. 2013. PMID: 23460909 Free PMC article.
HypoxamiRs: regulators of cardiac hypoxia and energy metabolism.
Azzouzi HE, Leptidis S, Doevendans PA, De Windt LJ. Azzouzi HE, et al. Among authors: leptidis s. Trends Endocrinol Metab. 2015 Sep;26(9):502-8. doi: 10.1016/j.tem.2015.06.008. Epub 2015 Jul 18. Trends Endocrinol Metab. 2015. PMID: 26197955 Review.
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.
Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ. Dirkx E, et al. Among authors: leptidis s. Nat Cell Biol. 2013 Nov;15(11):1282-93. doi: 10.1038/ncb2866. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161931
Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection.
el Azzouzi H, Leptidis S, Bourajjaj M, Armand AS, van der Nagel R, van Bilsen M, Da Costa Martins PA, De Windt LJ. el Azzouzi H, et al. Among authors: leptidis s. J Biol Chem. 2011 Apr 22;286(16):14598-607. doi: 10.1074/jbc.M111.220525. Epub 2011 Jan 18. J Biol Chem. 2011. PMID: 21245137 Free PMC article.
The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.
el Azzouzi H, Leptidis S, Dirkx E, Hoeks J, van Bree B, Brand K, McClellan EA, Poels E, Sluimer JC, van den Hoogenhof MM, Armand AS, Yin X, Langley S, Bourajjaj M, Olieslagers S, Krishnan J, Vooijs M, Kurihara H, Stubbs A, Pinto YM, Krek W, Mayr M, da Costa Martins PA, Schrauwen P, De Windt LJ. el Azzouzi H, et al. Among authors: leptidis s. Cell Metab. 2013 Sep 3;18(3):341-54. doi: 10.1016/j.cmet.2013.08.009. Cell Metab. 2013. PMID: 24011070 Free article.
MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.
da Costa Martins PA, Salic K, Gladka MM, Armand AS, Leptidis S, el Azzouzi H, Hansen A, Coenen-de Roo CJ, Bierhuizen MF, van der Nagel R, van Kuik J, de Weger R, de Bruin A, Condorelli G, Arbones ML, Eschenhagen T, De Windt LJ. da Costa Martins PA, et al. Among authors: leptidis s. Nat Cell Biol. 2010 Dec;12(12):1220-7. doi: 10.1038/ncb2126. Epub 2010 Nov 21. Nat Cell Biol. 2010. PMID: 21102440
16 results