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A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.
d'Avenia M, Citro R, De Marco M, Veronese A, Rosati A, Visone R, Leptidis S, Philippen L, Vitale G, Cavallo A, Silverio A, Prota C, Gravina P, De Cola A, Carletti E, Coppola G, Gallo S, Provenza G, Bossone E, Piscione F, Hahne M, De Windt LJ, Turco MC, De Laurenzi V. d'Avenia M, et al. Among authors: de marco m, de windt lj, de cola a, de laurenzi v. Cell Death Dis. 2015 Oct 29;6(10):e1948. doi: 10.1038/cddis.2015.280. Cell Death Dis. 2015. PMID: 26512958 Free PMC article.
MicroRNA regulation in cardiovascular disease.
da Costa Martins PA, Leptidis S, Salic K, De Windt LJ. da Costa Martins PA, et al. Among authors: de windt lj. Curr Drug Targets. 2010 Aug;11(8):900-6. doi: 10.2174/138945010791591322. Curr Drug Targets. 2010. PMID: 20415652 Review.
Peroxisome proliferator-activated receptor (PPAR) gene profiling uncovers insulin-like growth factor-1 as a PPARalpha target gene in cardioprotection.
el Azzouzi H, Leptidis S, Bourajjaj M, Armand AS, van der Nagel R, van Bilsen M, Da Costa Martins PA, De Windt LJ. el Azzouzi H, et al. Among authors: de windt lj. J Biol Chem. 2011 Apr 22;286(16):14598-607. doi: 10.1074/jbc.M111.220525. Epub 2011 Jan 18. J Biol Chem. 2011. PMID: 21245137 Free PMC article.
A deep sequencing approach to uncover the miRNOME in the human heart.
Leptidis S, El Azzouzi H, Lok SI, de Weger R, Olieslagers S, Kisters N, Silva GJ, Heymans S, Cuppen E, Berezikov E, De Windt LJ, da Costa Martins P. Leptidis S, et al. Among authors: de windt lj, de weger r. PLoS One. 2013;8(2):e57800. doi: 10.1371/journal.pone.0057800. Epub 2013 Feb 27. PLoS One. 2013. PMID: 23460909 Free PMC article.
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy.
Citro R, d'Avenia M, De Marco M, Giudice R, Mirra M, Ravera A, Silverio A, Farina R, Silvestri F, Gravina P, Villa F, Puca AA, De Windt L, De Laurenzi V, Bossone E, Turco MC, Piscione F. Citro R, et al. Int J Cardiol. 2013 Sep 30;168(2):1663-5. doi: 10.1016/j.ijcard.2013.03.050. Epub 2013 Apr 11. Int J Cardiol. 2013. PMID: 23582692 No abstract available.
The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.
el Azzouzi H, Leptidis S, Dirkx E, Hoeks J, van Bree B, Brand K, McClellan EA, Poels E, Sluimer JC, van den Hoogenhof MM, Armand AS, Yin X, Langley S, Bourajjaj M, Olieslagers S, Krishnan J, Vooijs M, Kurihara H, Stubbs A, Pinto YM, Krek W, Mayr M, da Costa Martins PA, Schrauwen P, De Windt LJ. el Azzouzi H, et al. Among authors: de windt lj. Cell Metab. 2013 Sep 3;18(3):341-54. doi: 10.1016/j.cmet.2013.08.009. Cell Metab. 2013. PMID: 24011070 Free article.
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.
Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ. Dirkx E, et al. Among authors: de windt lj, de weger r. Nat Cell Biol. 2013 Nov;15(11):1282-93. doi: 10.1038/ncb2866. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161931
Nuclear calcium transients: Hermes Propylaios in the heart.
da Costa Martins PA, Leptidis S, De Windt LJ. da Costa Martins PA, et al. Among authors: de windt lj. Circulation. 2014 Jul 15;130(3):221-3. doi: 10.1161/CIRCULATIONAHA.114.010675. Epub 2014 Jun 13. Circulation. 2014. PMID: 24928679 No abstract available.
160 results