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Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders.
Hobson AD, Harris CM, van der Kam EL, Turner SC, Abibi A, Aguirre AL, Bousquet P, Kebede T, Konopacki DB, Gintant G, Kim Y, Larson K, Maull JW, Moore NS, Shi D, Shrestha A, Tang X, Zhang P, Sarris KK. Hobson AD, et al. Among authors: shi d. J Med Chem. 2015 Dec 10;58(23):9154-70. doi: 10.1021/acs.jmedchem.5b00928. Epub 2015 Nov 23. J Med Chem. 2015. PMID: 26509640
Syk Inhibition Induces Platelet Dependent Peri-islet Hemorrhage in the Rat Pancreas.
Long AJ, Sampson E, McCarthy RW, Harris CM, Barnard M, Shi D, Conlon D, Caldwell R, Honor D, Wishart N, Hoemann M, Duggan L, Fritz D, Stedman C, O'Connor E, Mikaelian I, Schwartz A. Long AJ, et al. Among authors: shi d. Toxicol Pathol. 2016 Oct;44(7):998-1012. doi: 10.1177/0192623316654015. Epub 2016 Jun 19. Toxicol Pathol. 2016. PMID: 27324990
An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases.
McPherson MJ, Hobson AD, Hernandez A Jr, Marvin CC, Waegell W, Goess C, Oh JZ, Shi D, Hayes ME, Wang L, Wang L, Schmidt D, Wang Z, Pitney V, McCarthy K, Jia Y, Wang C, Kang BN, Bryant S, Mathieu S, Ruzek M, Parmentier J, D'Cunha RR, Pang Y, Phillips L, Brown NJ, Xu J, Graff C, Tian Y, Longenecker KL, Qiu W, Zhu H, Liu W, Zheng P, Bi Y, Stoffel R. McPherson MJ, et al. Among authors: d cunha rr, shi d. Sci Transl Med. 2024 Mar 20;16(739):eadd8936. doi: 10.1126/scitranslmed.add8936. Epub 2024 Mar 20. Sci Transl Med. 2024. PMID: 38507467
5,709 results