Fitzgerald ML - Search Results

1

LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.

Tamehiro N, Park MH, Hawxhurst V, Nagpal K, Adams ME, Zannis VI, Golenbock DT, Fitzgerald ML. Tamehiro N, et al. Among authors: fitzgerald ml. Biochemistry. 2015 Nov 24;54(46):6931-41. doi: 10.1021/acs.biochem.5b00894. Epub 2015 Nov 9. Biochemistry. 2015. PMID: 26506427 Free PMC article.

2

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.

Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW. Fitzgerald ML, et al. J Biol Chem. 2002 Sep 6;277(36):33178-87. doi: 10.1074/jbc.M204996200. Epub 2002 Jun 25. J Biol Chem. 2002. PMID: 12084722 Free article.

3

ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.

Fitzgerald ML, Morris AL, Chroni A, Mendez AJ, Zannis VI, Freeman MW. Fitzgerald ML, et al. J Lipid Res. 2004 Feb;45(2):287-94. doi: 10.1194/jlr.M300355-JLR200. Epub 2003 Nov 16. J Lipid Res. 2004. PMID: 14617740 Free article.

4

Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.

Chroni A, Liu T, Fitzgerald ML, Freeman MW, Zannis VI. Chroni A, et al. Among authors: fitzgerald ml. Biochemistry. 2004 Feb 24;43(7):2126-39. doi: 10.1021/bi035813p. Biochemistry. 2004. PMID: 14967052

5

Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide.

Nieland TJ, Chroni A, Fitzgerald ML, Maliga Z, Zannis VI, Kirchhausen T, Krieger M. Nieland TJ, et al. Among authors: fitzgerald ml. J Lipid Res. 2004 Jul;45(7):1256-65. doi: 10.1194/jlr.M300358-JLR200. Epub 2004 Apr 21. J Lipid Res. 2004. PMID: 15102890 Free article.

6

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.

Fitzgerald ML, Okuhira K, Short GF 3rd, Manning JJ, Bell SA, Freeman MW. Fitzgerald ML, et al. J Biol Chem. 2004 Nov 12;279(46):48477-85. doi: 10.1074/jbc.M409848200. Epub 2004 Sep 3. J Biol Chem. 2004. PMID: 15347662 Free article.

7

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.

Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW. Okuhira K, et al. Among authors: fitzgerald ml. J Biol Chem. 2005 Nov 25;280(47):39653-64. doi: 10.1074/jbc.M510187200. Epub 2005 Sep 28. J Biol Chem. 2005. PMID: 16192269 Free article.

8

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.

Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML. Tamehiro N, et al. Among authors: fitzgerald ml. Biochemistry. 2008 Jun 10;47(23):6138-47. doi: 10.1021/bi800182t. Epub 2008 May 17. Biochemistry. 2008. PMID: 18484747 Free PMC article.

9

Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.

Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML. Tamehiro N, et al. Among authors: fitzgerald ml. J Biol Chem. 2009 Sep 11;284(37):24881-90. doi: 10.1074/jbc.M109.014365. Epub 2009 Jul 10. J Biol Chem. 2009. PMID: 19592499 Free PMC article.

10

ABC transporters, atherosclerosis and inflammation.

Fitzgerald ML, Mujawar Z, Tamehiro N. Fitzgerald ML, et al. Atherosclerosis. 2010 Aug;211(2):361-70. doi: 10.1016/j.atherosclerosis.2010.01.011. Epub 2010 Jan 21. Atherosclerosis. 2010. PMID: 20138281 Free PMC article. Review.

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