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Photobac derived from bacteriochlorophyll-a shows potential for treating brain tumor in animal models by photodynamic therapy with desired pharmacokinetics and limited toxicity in rats and dogs.
Durrani FA, Cacaccio J, Turowski SG, Dukh M, Bshara W, Curtin L, Sexton S, Spernyak JA, Pandey RK. Durrani FA, et al. Among authors: spernyak ja. Biomed Pharmacother. 2023 Dec;168:115731. doi: 10.1016/j.biopha.2023.115731. Epub 2023 Oct 17. Biomed Pharmacother. 2023. PMID: 37857248 Free PMC article.
Iron(II) PARACEST MRI contrast agents.
Dorazio SJ, Tsitovich PB, Siters KE, Spernyak JA, Morrow JR. Dorazio SJ, et al. Among authors: spernyak ja. J Am Chem Soc. 2011 Sep 14;133(36):14154-6. doi: 10.1021/ja204297z. Epub 2011 Aug 18. J Am Chem Soc. 2011. PMID: 21838276 Free PMC article.
The NiCEST approach: nickel(II) paraCEST MRI contrast agents.
Olatunde AO, Dorazio SJ, Spernyak JA, Morrow JR. Olatunde AO, et al. Among authors: spernyak ja. J Am Chem Soc. 2012 Nov 14;134(45):18503-5. doi: 10.1021/ja307909x. Epub 2012 Nov 2. J Am Chem Soc. 2012. PMID: 23102112
CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents.
Dorazio SJ, Olatunde AO, Spernyak JA, Morrow JR. Dorazio SJ, et al. Among authors: spernyak ja. Chem Commun (Camb). 2013 Nov 4;49(85):10025-7. doi: 10.1039/c3cc45000g. Chem Commun (Camb). 2013. PMID: 24045271 Free PMC article.
62 results