You Q - Search Results

1

Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: introduction of an additional carboxyl group at the C-2 position of quinoline.

Feng T, Li D, Wang H, Zhuang J, Liu F, Bao Q, Lei Y, Chen W, Zhang X, Xu X, Sun H, You Q, Guo X. Feng T, et al. Among authors: you q. Eur J Med Chem. 2015 Nov 13;105:145-55. doi: 10.1016/j.ejmech.2015.09.013. Epub 2015 Sep 10. Eur J Med Chem. 2015. PMID: 26491978

2

The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.

Du LP, Tsai KC, Li MY, You QD, Xia L. Du LP, et al. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4771-7. doi: 10.1016/j.bmcl.2004.06.070. Bioorg Med Chem Lett. 2004. PMID: 15324906

3

Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase.

Cao X, You QD, Li ZY, Guo QL, Shang J, Yan M, Chern JW, Chen ML. Cao X, et al. Bioorg Med Chem. 2008 Jun 1;16(11):5890-8. doi: 10.1016/j.bmc.2008.04.065. Epub 2008 Apr 29. Bioorg Med Chem. 2008. PMID: 18485715

4

Novel hexacyclic camptothecin derivatives. Part 1: synthesis and cytotoxicity of camptothecins with an A-ring fused 1,3-oxazine ring.

Wang S, Li Y, Liu Y, Lu A, You Q. Wang S, et al. Among authors: you q. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4095-7. doi: 10.1016/j.bmcl.2008.05.103. Epub 2008 Jun 12. Bioorg Med Chem Lett. 2008. PMID: 18554906

5

Design, synthesis and biological evaluation of novel compounds with conjugated structure as anti-tumor agents.

Su H, Nebbioso A, Carafa V, Chen Y, Yang B, Altucci L, You Q. Su H, et al. Among authors: you q. Bioorg Med Chem. 2008 Sep 1;16(17):7992-8002. doi: 10.1016/j.bmc.2008.07.066. Epub 2008 Jul 29. Bioorg Med Chem. 2008. PMID: 18701301

6

Recent progress of SRC family kinase inhibitors as anticancer agents.

Cao X, You QD, Li ZY, Wang XJ, Lu XY, Liu XR, Xu D, Liu B. Cao X, et al. Mini Rev Med Chem. 2008 Sep;8(10):1053-63. doi: 10.2174/138955708785740634. Mini Rev Med Chem. 2008. PMID: 18782057 Review.

7

The design, synthesis and biological evaluation of 7-alkoxy-4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS.

Cao X, You QD, Li ZY, Liu XR, Xu D, Guo QL, Shang J, Chern JW, Chen ML. Cao X, et al. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6206-9. doi: 10.1016/j.bmcl.2008.10.006. Epub 2008 Oct 5. Bioorg Med Chem Lett. 2008. PMID: 18930653

8

Studies on chemical structure modification and biology of a natural product, gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid.

Wang J, Zhao L, Hu Y, Guo Q, Zhang L, Wang X, Li N, You Q. Wang J, et al. Among authors: you q. Eur J Med Chem. 2009 Jun;44(6):2611-20. doi: 10.1016/j.ejmech.2008.09.034. Epub 2008 Oct 7. Eur J Med Chem. 2009. PMID: 18996626

9

Design and synthesis of N-methylmaleimide indolocarbazole bearing modified 2-acetamino acid moieties as Topoisomerase I inhibitors.

Li Z, Zhai F, Zhao L, Guo Q, You Q. Li Z, et al. Among authors: you q. Bioorg Med Chem Lett. 2009 Jan 15;19(2):406-9. doi: 10.1016/j.bmcl.2008.11.061. Epub 2008 Nov 21. Bioorg Med Chem Lett. 2009. PMID: 19058964

10

3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment.

Chen Y, Li H, Tang W, Zhu C, Jiang Y, Zou J, Yu Q, You Q. Chen Y, et al. Among authors: you q. Eur J Med Chem. 2009 Jul;44(7):2868-76. doi: 10.1016/j.ejmech.2008.12.008. Epub 2008 Dec 16. Eur J Med Chem. 2009. PMID: 19136179

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