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Page 1
α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.
Pribasnig MA, Mrak I, Grabner GF, Taschler U, Knittelfelder O, Scherz B, Eichmann TO, Heier C, Grumet L, Kowaliuk J, Romauch M, Holler S, Anderl F, Wolinski H, Lass A, Breinbauer R, Marsche G, Brown JM, Zimmermann R. Pribasnig MA, et al. Among authors: eichmann to. J Biol Chem. 2015 Dec 11;290(50):29869-81. doi: 10.1074/jbc.M115.669168. Epub 2015 Oct 21. J Biol Chem. 2015. PMID: 26491015 Free PMC article.
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila PP, Wohlwend M, Imamura de Lima T, Luan P, Herzig S, Zanou N, Crisol B, Bou-Sleiman M, Porcu E, Gallart-Ayala H, Handzlik MK, Wang Q, Jain S, D'Amico D, Salonen M, Metallo CM, Kutalik Z, Eichmann TO, Place N, Ivanisevic J, Lahti J, Eriksson JG, Auwerx J. Laurila PP, et al. Among authors: eichmann to. Nat Aging. 2022 Dec;2(12):1159-1175. doi: 10.1038/s43587-022-00309-6. Epub 2022 Dec 16. Nat Aging. 2022. PMID: 37118545
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids.
Schoiswohl G, Schweiger M, Schreiber R, Gorkiewicz G, Preiss-Landl K, Taschler U, Zierler KA, Radner FP, Eichmann TO, Kienesberger PC, Eder S, Lass A, Haemmerle G, Alsted TJ, Kiens B, Hoefler G, Zechner R, Zimmermann R. Schoiswohl G, et al. Among authors: eichmann to. J Lipid Res. 2010 Mar;51(3):490-9. doi: 10.1194/jlr.M001073. Epub 2009 Nov 25. J Lipid Res. 2010. PMID: 19965578 Free PMC article.
Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
Radner FP, Streith IE, Schoiswohl G, Schweiger M, Kumari M, Eichmann TO, Rechberger G, Koefeler HC, Eder S, Schauer S, Theussl HC, Preiss-Landl K, Lass A, Zimmermann R, Hoefler G, Zechner R, Haemmerle G. Radner FP, et al. Among authors: eichmann to. J Biol Chem. 2010 Mar 5;285(10):7300-11. doi: 10.1074/jbc.M109.081877. Epub 2009 Dec 18. J Biol Chem. 2010. PMID: 20023287 Free PMC article.
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. Haemmerle G, et al. Nat Med. 2011 Aug 21;17(9):1076-85. doi: 10.1038/nm.2439. Nat Med. 2011. PMID: 21857651 Free PMC article.
Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
Etschmaier K, Becker T, Eichmann TO, Schweinzer C, Scholler M, Tam-Amersdorfer C, Poeckl M, Schuligoi R, Kober A, Chirackal Manavalan AP, Rechberger GN, Streith IE, Zechner R, Zimmermann R, Panzenboeck U. Etschmaier K, et al. Among authors: eichmann to. J Neurochem. 2011 Dec;119(5):1016-28. doi: 10.1111/j.1471-4159.2011.07498.x. Epub 2011 Oct 20. J Neurochem. 2011. PMID: 21951135 Free article.
FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.
Zechner R, Zimmermann R, Eichmann TO, Kohlwein SD, Haemmerle G, Lass A, Madeo F. Zechner R, et al. Among authors: eichmann to. Cell Metab. 2012 Mar 7;15(3):279-91. doi: 10.1016/j.cmet.2011.12.018. Cell Metab. 2012. PMID: 22405066 Free PMC article. Review.
Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Mayer N, Schweiger M, Romauch M, Grabner GF, Eichmann TO, Fuchs E, Ivkovic J, Heier C, Mrak I, Lass A, Höfler G, Fledelius C, Zechner R, Zimmermann R, Breinbauer R. Mayer N, et al. Among authors: eichmann to. Nat Chem Biol. 2013 Dec;9(12):785-7. doi: 10.1038/nchembio.1359. Epub 2013 Oct 6. Nat Chem Biol. 2013. PMID: 24096302 Free PMC article.
79 results