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Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.
Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, Aronow B, Fang G, Zhang B, Cotter D, Brennand KJ. Topol A, et al. Among authors: brennand kj. Transl Psychiatry. 2015 Oct 20;5(10):e662. doi: 10.1038/tp.2015.118. Transl Psychiatry. 2015. PMID: 26485546 Free PMC article.
Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala.
Hicks EM, Seah C, Deans M, Lee S, Johnston KJA, Cote A, Ciarcia J, Chakka A, Collier L, Holtzheimer PE, Young KA; Traumatic Stress Brain Research Group; Krystal JH, Brennand KJ, Nestler EJ, Girgenti MJ, Huckins LM. Hicks EM, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2024 Oct 23:2024.10.23.619681. doi: 10.1101/2024.10.23.619681. bioRxiv. 2024. PMID: 39484441 Free PMC article. Preprint.
MASTR-seq: Multiplexed Analysis of Short Tandem Repeats with sequencing.
Su C, Chandradoss KR, Malachowski T, Boya R, Ryu HS, Brennand KJ, Phillips-Cremins JE. Su C, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2024 May 2:2024.04.29.591790. doi: 10.1101/2024.04.29.591790. bioRxiv. 2024. PMID: 38746155 Free PMC article. Preprint.
Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder.
Mishra HK, Wei H, Rohr KE, Ko I, Nievergelt CM, Maihofer AX, Shilling PD, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Frye M, Gage F, Gershon E, McInnis MG, Nurnberger J, Oedegaard KJ, Zandi PP, Kelsoe JR, McCarthy MJ. Mishra HK, et al. Among authors: brennand kj. Eur Neuropsychopharmacol. 2023 Sep;74:1-14. doi: 10.1016/j.euroneuro.2023.04.009. Epub 2023 Apr 29. Eur Neuropsychopharmacol. 2023. PMID: 37126998
Dynamic convergence of autism disorder risk genes across neurodevelopment.
Garcia MF, Retallick-Townsley K, Pruitt A, Davidson E, Dai Y, Fitzpatrick SE, Sen A, Cohen S, Livoti O, Khan S, Dossou G, Cheung J, Deans PJM, Wang Z, Huckins L, Hoffman E, Brennand K. Garcia MF, et al. bioRxiv [Preprint]. 2024 Aug 24:2024.08.23.609190. doi: 10.1101/2024.08.23.609190. bioRxiv. 2024. PMID: 39229156 Free PMC article. Preprint.
Common genetic variation impacts stress response in the brain.
Seah C, Signer R, Deans M, Bader H, Rusielewicz T, Hicks EM, Young H, Cote A, Townsley K, Xu C, Hunter CJ, McCarthy B, Goldberg J, Dobariya S, Holtzherimer PE, Young KA; NYSCF Global Stem Cell Array® Team; Traumatic Stress Brain Research Group; Noggle SA, Krystal JH, Paull D, Girgenti MJ, Yehuda R, Brennand KJ, Huckins LM. Seah C, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2023 Dec 28:2023.12.27.573459. doi: 10.1101/2023.12.27.573459. bioRxiv. 2023. PMID: 38234801 Free PMC article. Preprint.
Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain.
Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Matoba N, Tang M, Jiao C, Kim M, Tsai E, Hoh C, Aygün N, Walker RL, Chatzinakos C, Clarke D, Pratt H; PsychENCODE Consortium†; Peters MA, Gerstein M, Daskalakis NP, Weng Z, Jaffe AE, Kleinman JE, Hyde TM, Weinberger DR, Bray NJ, Sestan N, Geschwind DH, Roeder K, Gusev A, Pasaniuc B, Stein JL, Love MI, Pollard KS, Liu C, Gandal MJ; PsychENCODE Consortium. Wen C, et al. Science. 2024 May 24;384(6698):eadh0829. doi: 10.1126/science.adh0829. Epub 2024 May 24. Science. 2024. PMID: 38781368
Dynamic stress- and inflammatory-based regulation of psychiatric risk loci in human neurons.
Retallick-Townsley KG, Lee S, Cartwright S, Cohen S, Sen A, Jia M, Young H, Dobbyn L, Deans M, Fernandez-Garcia M, Huckins LM, Brennand KJ. Retallick-Townsley KG, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2024 Jul 9:2024.07.09.602755. doi: 10.1101/2024.07.09.602755. bioRxiv. 2024. PMID: 39026810 Free PMC article. Preprint.
The functional and evolutionary impacts of human-specific deletions in conserved elements.
Xue JR, Mackay-Smith A, Mouri K, Garcia MF, Dong MX, Akers JF, Noble M, Li X; Zoonomia Consortium†; Lindblad-Toh K, Karlsson EK, Noonan JP, Capellini TD, Brennand KJ, Tewhey R, Sabeti PC, Reilly SK. Xue JR, et al. Among authors: brennand kj. Science. 2023 Apr 28;380(6643):eabn2253. doi: 10.1126/science.abn2253. Epub 2023 Apr 28. Science. 2023. PMID: 37104592 Free PMC article.
158 results