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A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity.
Moine E, Denevault-Sabourin C, Debierre-Grockiego F, Silpa L, Gorgette O, Barale JC, Jacquiet P, Brossier F, Gueiffier A, Dimier-Poisson I, Enguehard-Gueiffier C. Moine E, et al. Eur J Med Chem. 2015 Jan 7;89:386-400. doi: 10.1016/j.ejmech.2014.10.057. Epub 2014 Oct 22. Eur J Med Chem. 2015. PMID: 25462254
Imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1 decrease the parasite burden in mice with acute toxoplasmosis.
Moine E, Moiré N, Dimier-Poisson I, Brunet K, Couet W, Colas C, Van Langendonck N, Enguehard-Gueiffier C, Gueiffier A, Héraut B, Denevault-Sabourin C, Debierre-Grockiego F. Moine E, et al. Int J Parasitol. 2018 Jun;48(7):561-568. doi: 10.1016/j.ijpara.2017.12.006. Epub 2018 Mar 7. Int J Parasitol. 2018. PMID: 29524527
Targeted Lipidomics Profiling Reveals the Generation of Hydroxytyrosol-Fatty Acids in Hydroxytyrosol-Fortified Oily Matrices: New Analytical Methodology and Cytotoxicity Evaluation.
Medina S, Domínguez-Perles R, Auñón D, Moine E, Durand T, Crauste C, Ferreres F, Gil-Izquierdo Á. Medina S, et al. Among authors: moine e. J Agric Food Chem. 2020 Jul 22;68(29):7789-7799. doi: 10.1021/acs.jafc.0c01938. Epub 2020 Jul 10. J Agric Food Chem. 2020. PMID: 32603105
Fatty Acid Hydroxytyrosyl Esters of Olive Oils Are Bioaccessible According to Simulated In Vitro Gastrointestinal Digestion: Unraveling the Role of Digestive Enzymes on Their Stability.
Alemán-Jiménez C, Domínguez-Perles R, Gallego-Gómez JI, Simonelli-Muñoz A, Moine E, Durand T, Crauste C, Ferreres F, Gil-Izquierdo Á, Medina S. Alemán-Jiménez C, et al. Among authors: moine e. J Agric Food Chem. 2021 Dec 1;69(47):14165-14175. doi: 10.1021/acs.jafc.1c05373. Epub 2021 Nov 19. J Agric Food Chem. 2021. PMID: 34797062
13 results