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In vitro and in vivo trypanocidal activity of H2bdtc-loaded solid lipid nanoparticles.
Carneiro ZA, Maia PI, Sesti-Costa R, Lopes CD, Pereira TA, Milanezi CM, da Silva MA, Lopez RF, Silva JS, Deflon VM. Carneiro ZA, et al. Among authors: lopes cd. PLoS Negl Trop Dis. 2014 May 8;8(5):e2847. doi: 10.1371/journal.pntd.0002847. eCollection 2014 May. PLoS Negl Trop Dis. 2014. PMID: 24810753 Free PMC article.
Click chemistry oligomerisation of azido-alkyne-functionalised galactose accesses triazole-linked linear oligomers and macrocycles that inhibit Trypanosoma cruzi macrophage invasion.
Campo VL, Ivanova IM, Carvalho I, Lopes CD, Carneiro ZA, Saalbach G, Schenkman S, da Silva JS, Nepogodiev SA, Field RA. Campo VL, et al. Among authors: lopes cd. Tetrahedron. 2015 Sep 30;71(39):7344-7353. doi: 10.1016/j.tet.2015.04.085. Tetrahedron. 2015. PMID: 26435551 Free PMC article.
Synthesis and 2D-QSAR studies of neolignan-based diaryl-tetrahydrofuran and -furan analogues with remarkable activity against Trypanosoma cruzi and assessment of the trypanothione reductase activity.
Hartmann AP, de Carvalho MR, Bernardes LSC, Moraes MH, de Melo EB, Lopes CD, Steindel M, da Silva JS, Carvalho I. Hartmann AP, et al. Among authors: lopes cd. Eur J Med Chem. 2017 Nov 10;140:187-199. doi: 10.1016/j.ejmech.2017.08.064. Epub 2017 Sep 4. Eur J Med Chem. 2017. PMID: 28926763
Three new platinum complexes containing fluoroquinolones and DMSO: Cytotoxicity and evaluation against drug-resistant tuberculosis.
de Oliveira LP, Carneiro ZA, Ribeiro CM, Lima MF, Paixão DA, Pivatto M, de Souza MVN, Teixeira LR, Lopes CD, de Albuquerque S, Pavan FR, Guerra W. de Oliveira LP, et al. Among authors: lopes cd. J Inorg Biochem. 2018 Jun;183:77-83. doi: 10.1016/j.jinorgbio.2018.03.010. Epub 2018 Mar 16. J Inorg Biochem. 2018. PMID: 29567518
Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis.
Silva MC, Davoli-Ferreira M, Medina TS, Sesti-Costa R, Silva GK, Lopes CD, Cardozo LE, Gava FN, Lyroni K, Dias FC, Frade AF, Baron M, Nakaya HI, Figueiredo F, Alves-Filho JC, Cunha FQ, Tsatsanis C, Chevillard C, Cunha-Neto E, Hirsch E, Silva JS, Cunha TM. Silva MC, et al. Among authors: lopes cd. Nat Commun. 2018 Apr 17;9(1):1513. doi: 10.1038/s41467-018-03986-3. Nat Commun. 2018. PMID: 29666415 Free PMC article.
In vitro anti-Trypanosoma cruzi activity of ternary copper(II) complexes and in vivo evaluation of the most promising complex.
Paixão DA, Lopes CD, Carneiro ZA, Sousa LM, de Oliveira LP, Lopes NP, Pivatto M, Chaves JDS, de Almeida MV, Ellena J, Moreira MB, Netto AVG, de Oliveira RJ, Guilardi S, de Albuquerque S, Guerra W. Paixão DA, et al. Among authors: lopes np, lopes cd. Biomed Pharmacother. 2019 Jan;109:157-166. doi: 10.1016/j.biopha.2018.10.057. Epub 2018 Nov 2. Biomed Pharmacother. 2019. PMID: 30396072 Free article.
Heterobimetallic nickel(II) and palladium(II) complexes derived from S-benzyl-N- (ferrocenyl)methylenedithiocarbazate: Trypanocidal activity and interaction with Trypanosoma cruzi Old Yellow Enzyme (TcOYE).
Carneiro ZA, Lima JC, Lopes CD, Gaspari APS, de Albuquerque S, Dinelli LR, Veloso-Silva LLW, Paganelli MO, Libardi SH, Oliveira CG, Deflon VM, Oliveira RJ, Borges JC, Maia PIS. Carneiro ZA, et al. Among authors: lopes cd. Eur J Med Chem. 2019 Oct 15;180:213-223. doi: 10.1016/j.ejmech.2019.07.014. Epub 2019 Jul 5. Eur J Med Chem. 2019. PMID: 31306908
64 results