Smith MW - Search Results

1

Absorption of ipratropium and l-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN transporters.

Al-Jayyoussi G, Price DF, Kreitmeyr K, Keogh JP, Smith MW, Gumbleton M, Morris CJ. Al-Jayyoussi G, et al. Among authors: smith mw. Int J Pharm. 2015 Dec 30;496(2):834-41. doi: 10.1016/j.ijpharm.2015.10.036. Epub 2015 Oct 22. Int J Pharm. 2015. PMID: 26475971

2

Endocytosis at the blood-brain barrier: from basic understanding to drug delivery strategies.

Smith MW, Gumbleton M. Smith MW, et al. J Drug Target. 2006 May;14(4):191-214. doi: 10.1080/10611860600650086. J Drug Target. 2006. PMID: 16777679 Review.

3

Phage display identification of functional binding peptides against 4-acetamidophenol (Paracetamol): an exemplified approach to target low molecular weight organic molecules.

Smith MW, Smith JW, Harris C, Brancale A, Allender CJ, Gumbleton M. Smith MW, et al. Among authors: smith jw. Biochem Biophys Res Commun. 2007 Jun 22;358(1):285-91. doi: 10.1016/j.bbrc.2007.04.122. Epub 2007 Apr 27. Biochem Biophys Res Commun. 2007. PMID: 17482566

4

Primary porcine brain microvascular endothelial cells: biochemical and functional characterisation as a model for drug transport and targeting.

Smith M, Omidi Y, Gumbleton M. Smith M, et al. J Drug Target. 2007 May;15(4):253-68. doi: 10.1080/10611860701288539. J Drug Target. 2007. PMID: 17487694

5

Cell selective glucocorticoid induction of caveolin-1 and caveolae in differentiating pulmonary alveolar epithelial cell cultures.

Barar J, Campbell L, Hollins AJ, Thomas NP, Smith MW, Morris CJ, Gumbleton M. Barar J, et al. Among authors: smith mw. Biochem Biophys Res Commun. 2007 Jul 27;359(2):360-6. doi: 10.1016/j.bbrc.2007.05.106. Epub 2007 May 24. Biochem Biophys Res Commun. 2007. PMID: 17537407

6

Spatial expression and functionality of drug transporters in the intact lung: objectives for further research.

Gumbleton M, Al-Jayyoussi G, Crandon-Lewis A, Francombe D, Kreitmeyr K, Morris CJ, Smith MW. Gumbleton M, et al. Among authors: smith mw. Adv Drug Deliv Rev. 2011 Jan-Feb;63(1-2):110-8. doi: 10.1016/j.addr.2010.09.008. Epub 2010 Sep 22. Adv Drug Deliv Rev. 2011. PMID: 20868712 Review.

7

Enhanced pulmonary absorption of a macromolecule through coupling to a sequence-specific phage display-derived peptide.

Morris CJ, Smith MW, Griffiths PC, McKeown NB, Gumbleton M. Morris CJ, et al. Among authors: smith mw. J Control Release. 2011 Apr 10;151(1):83-94. doi: 10.1016/j.jconrel.2010.12.003. Epub 2010 Dec 20. J Control Release. 2011. PMID: 21182881

8

Peptide sequences mediating tropism to intact blood-brain barrier: an in vivo biodistribution study using phage display.

Smith MW, Al-Jayyoussi G, Gumbleton M. Smith MW, et al. Peptides. 2012 Nov;38(1):172-80. doi: 10.1016/j.peptides.2012.06.019. Epub 2012 Aug 28. Peptides. 2012. PMID: 22955033

9

Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: a study in ex vivo lung models using chemical inhibition and genetic knockout.

Al-Jayyoussi G, Price DF, Francombe D, Taylor G, Smith MW, Morris C, Edwards CD, Eddershaw P, Gumbleton M. Al-Jayyoussi G, et al. Among authors: smith mw. J Pharm Sci. 2013 Sep;102(9):3382-94. doi: 10.1002/jps.23587. Epub 2013 May 13. J Pharm Sci. 2013. PMID: 23670704

10

Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease.

Campbell L, Al-Jayyoussi G, Gutteridge R, Gumbleton N, Griffiths R, Gumbleton S, Smith MW, Griffiths DF, Gumbleton M. Campbell L, et al. Among authors: smith mw. J Transl Med. 2013 Oct 11;11:255. doi: 10.1186/1479-5876-11-255. J Transl Med. 2013. PMID: 24119769 Free PMC article.

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