Finkler C - Search Results

1

Factors Governing the Precision of Subvisible Particle Measurement Methods - A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe.

Ríos Quiroz A, Lamerz J, Da Cunha T, Boillon A, Adler M, Finkler C, Huwyler J, Schmidt R, Mahler HC, Koulov AV. Ríos Quiroz A, et al. Among authors: finkler c. Pharm Res. 2016 Feb;33(2):450-61. doi: 10.1007/s11095-015-1801-4. Epub 2015 Oct 16. Pharm Res. 2016. PMID: 26474763

2

Measuring Subvisible Particles in Protein Formulations Using a Modified Light Obscuration Sensor with Improved Detection Capabilities.

Ríos Quiroz A, Québatte G, Stump F, Finkler C, Huwyler J, Schmidt R, Mahler HC, Koulov AV, Adler M. Ríos Quiroz A, et al. Among authors: finkler c. Anal Chem. 2015 Jun 16;87(12):6119-24. doi: 10.1021/acs.analchem.5b00688. Epub 2015 Jun 2. Anal Chem. 2015. PMID: 26001042

3

Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule.

Folzer E, Diepold K, Bomans K, Finkler C, Schmidt R, Bulau P, Huwyler J, Mahler HC, Koulov AV. Folzer E, et al. Among authors: finkler c. J Pharm Sci. 2015 Sep;104(9):2824-31. doi: 10.1002/jps.24509. Epub 2015 May 25. J Pharm Sci. 2015. PMID: 26010344

4

Comparative Evaluation of Two Methods for Preparative Fractionation of Proteinaceous Subvisible Particles--Differential Centrifugation and FACS.

Boll B, Folzer E, Finkler C, Huwyler J, Mahler HC, Schmidt R, Koulov AV. Boll B, et al. Among authors: finkler c. Pharm Res. 2015 Dec;32(12):3952-64. doi: 10.1007/s11095-015-1755-6. Epub 2015 Jul 21. Pharm Res. 2015. PMID: 26195006

5

Determination of the Density of Protein Particles Using a Suspended Microchannel Resonator.

Folzer E, Khan TA, Schmidt R, Finkler C, Huwyler J, Mahler HC, Koulov AV. Folzer E, et al. Among authors: finkler c. J Pharm Sci. 2015 Dec;104(12):4034-4040. doi: 10.1002/jps.24635. Epub 2015 Sep 7. J Pharm Sci. 2015. PMID: 26344825

6

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.

Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V. Plath F, et al. Among authors: finkler c. MAbs. 2016 Jul;8(5):928-40. doi: 10.1080/19420862.2016.1168960. Epub 2016 Mar 31. MAbs. 2016. PMID: 27031922 Free PMC article.

7

A Biopharmaceutical Industry Perspective on the Control of Visible Particles in Biotechnology-Derived Injectable Drug Products.

Mathonet S, Mahler HC, Esswein ST, Mazaheri M, Cash PW, Wuchner K, Kallmeyer G, Das TK, Finkler C, Lennard A. Mathonet S, et al. Among authors: finkler c. PDA J Pharm Sci Technol. 2016 Jul-Aug;70(4):392-408. doi: 10.5731/pdajpst.2015.006189. Epub 2016 Apr 18. PDA J Pharm Sci Technol. 2016. PMID: 27091885 Review.

8

Factors Governing the Accuracy of Subvisible Particle Counting Methods.

Ríos Quiroz A, Finkler C, Huwyler J, Mahler HC, Schmidt R, Koulov AV. Ríos Quiroz A, et al. Among authors: finkler c. J Pharm Sci. 2016 Jul;105(7):2042-52. doi: 10.1016/j.xphs.2016.03.044. Epub 2016 Jun 8. J Pharm Sci. 2016. PMID: 27287519

9

Extensive Chemical Modifications in the Primary Protein Structure of IgG1 Subvisible Particles Are Necessary for Breaking Immune Tolerance.

Boll B, Bessa J, Folzer E, Ríos Quiroz A, Schmidt R, Bulau P, Finkler C, Mahler HC, Huwyler J, Iglesias A, Koulov AV. Boll B, et al. Among authors: finkler c. Mol Pharm. 2017 Apr 3;14(4):1292-1299. doi: 10.1021/acs.molpharmaceut.6b00816. Epub 2017 Mar 7. Mol Pharm. 2017. PMID: 28206769

10

Impact of non-ideal analyte behavior on the separation of protein aggregates by asymmetric flow field-flow fractionation.

Boll B, Josse L, Heubach A, Hochenauer S, Finkler C, Huwyler J, Koulov AV. Boll B, et al. Among authors: finkler c. J Sep Sci. 2018 Jul;41(13):2854-2864. doi: 10.1002/jssc.201701457. J Sep Sci. 2018. PMID: 29696794

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