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Semysinthetic biflavonoid Morelloflavone-7,4',7″,3‴,4‴-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kexin PC1/3 than Kex2 and Furin.
de Souza AA, de Andrade DM, Siqueira FDS, Di Iorio JF, Veloso MP, Coelho CM, Viegas Junior C, Gontijo VS, Dos Santos MH, Meneghetti MCZ, Nader HB, Tersariol ILDS, Juliano L, Juliano MA, Judice WAS. de Souza AA, et al. Among authors: judice was. Biochim Biophys Acta Gen Subj. 2021 Dec;1865(12):130016. doi: 10.1016/j.bbagen.2021.130016. Epub 2021 Sep 22. Biochim Biophys Acta Gen Subj. 2021. PMID: 34560176
Oximic compounds as potential inhibitors of metacaspase-2 (TbMCA2) of Trypanosoma brucei.
Araujo LH, Bueno Chagas TA, Reis T, de Morais Borba JRB, Trujilho MNR, Dalzoto LAM, Marcondes MF, Juliano MA, Júdice WAS, Veloso MP, Machado MFM. Araujo LH, et al. Among authors: judice was. Biochem Biophys Res Commun. 2024 Nov 26;735:150657. doi: 10.1016/j.bbrc.2024.150657. Epub 2024 Sep 5. Biochem Biophys Res Commun. 2024. PMID: 39265363
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