Austin CA - Search Results

1

Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells.

Manville CM, Smith K, Sondka Z, Rance H, Cockell S, Cowell IG, Lee KC, Morris NJ, Padget K, Jackson GH, Austin CA. Manville CM, et al. Among authors: austin ca. Biol Open. 2015 Oct 12;4(11):1436-47. doi: 10.1242/bio.014308. Biol Open. 2015. PMID: 26459242 Free PMC article.

2

Self-association of chromo domain peptides.

Cowell IG, Austin CA. Cowell IG, et al. Among authors: austin ca. Biochim Biophys Acta. 1997 Feb 8;1337(2):198-206. doi: 10.1016/s0167-4838(96)00165-3. Biochim Biophys Acta. 1997. PMID: 9048896

3

Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique.

Willmore E, Frank AJ, Padget K, Tilby MJ, Austin CA. Willmore E, et al. Among authors: austin ca. Mol Pharmacol. 1998 Jul;54(1):78-85. doi: 10.1124/mol.54.1.78. Mol Pharmacol. 1998. PMID: 9658192

4

Nuclear distribution of human DNA topoisomerase IIbeta: a nuclear targeting signal resides in the 116-residue C-terminal tail.

Cowell IG, Willmore E, Chalton D, Marsh KL, Jazrawi E, Fisher LM, Austin CA. Cowell IG, et al. Among authors: austin ca. Exp Cell Res. 1998 Sep 15;243(2):232-40. doi: 10.1006/excr.1998.4150. Exp Cell Res. 1998. PMID: 9743583

5

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.

Cowell IG, Okorokov AL, Cutts SA, Padget K, Bell M, Milner J, Austin CA. Cowell IG, et al. Among authors: austin ca. Exp Cell Res. 2000 Feb 25;255(1):86-94. doi: 10.1006/excr.1999.4772. Exp Cell Res. 2000. PMID: 10666337

6

Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining).

Padget K, Carr R, Pearson AD, Tilby MJ, Austin CA. Padget K, et al. Among authors: austin ca. Biochem Pharmacol. 2000 Mar 15;59(6):629-38. doi: 10.1016/s0006-2952(99)00372-x. Biochem Pharmacol. 2000. PMID: 10677579

7

An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2, 1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells.

Padget K, Stewart A, Charlton P, Tilby MJ, Austin CA. Padget K, et al. Among authors: austin ca. Biochem Pharmacol. 2000 Sep 15;60(6):817-21. doi: 10.1016/s0006-2952(00)00402-0. Biochem Pharmacol. 2000. PMID: 10930536

8

Quantitation of DNA topoisomerase IIalpha and beta in human leukaemia cells by immunoblotting.

Padget K, Pearson AD, Austin CA. Padget K, et al. Among authors: austin ca. Leukemia. 2000 Nov;14(11):1997-2005. doi: 10.1038/sj.leu.2401928. Leukemia. 2000. PMID: 11069037

9

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.

Willmore E, de Caux S, Sunter NJ, Tilby MJ, Jackson GH, Austin CA, Durkacz BW. Willmore E, et al. Among authors: austin ca. Blood. 2004 Jun 15;103(12):4659-65. doi: 10.1182/blood-2003-07-2527. Epub 2004 Mar 9. Blood. 2004. PMID: 15010369 Free article.

10

mAMSA resistant human topoisomerase IIbeta mutation G465D has reduced ATP hydrolysis activity.

Gilroy KL, Leontiou C, Padget K, Lakey JH, Austin CA. Gilroy KL, et al. Among authors: austin ca. Nucleic Acids Res. 2006 Mar 20;34(5):1597-607. doi: 10.1093/nar/gkl057. Print 2006. Nucleic Acids Res. 2006. PMID: 16549872 Free PMC article.

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