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JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.
Pangon L, Ng I, Giry-Laterriere M, Currey N, Morgan A, Benthani F, Tran PN, Al-Sohaily S, Segelov E, Parker BL, Cowley MJ, Wright DC, St Heaps L, Carey L, Rooman I, Kohonen-Corish MR. Pangon L, et al. Among authors: parker bl. Oncogene. 2016 Jun 2;35(22):2834-41. doi: 10.1038/onc.2015.347. Epub 2015 Oct 12. Oncogene. 2016. PMID: 26455321
Personalized phosphoproteomics of skeletal muscle insulin resistance and exercise links MINDY1 to insulin action.
Needham EJ, Hingst JR, Onslev JD, Diaz-Vegas A, Leandersson MR, Huckstep H, Kristensen JM, Kido K, Richter EA, Højlund K, Parker BL, Cooke K, Yang G, Pehmøller C, Humphrey SJ, James DE, Wojtaszewski JFP. Needham EJ, et al. Among authors: parker bl. Cell Metab. 2024 Dec 3;36(12):2542-2559.e6. doi: 10.1016/j.cmet.2024.10.020. Epub 2024 Nov 21. Cell Metab. 2024. PMID: 39577414 Free article.
Pathogenic hypothalamic extracellular matrix promotes metabolic disease.
Beddows CA, Shi F, Horton AL, Dalal S, Zhang P, Ling CC, Yong VW, Loh K, Cho E, Karagiannis C, Rose AJ, Montgomery MK, Gregorevic P, Watt MJ, Packer NH, Parker BL, Brown RM, Moh ESX, Dodd GT. Beddows CA, et al. Among authors: parker bl. Nature. 2024 Sep;633(8031):914-922. doi: 10.1038/s41586-024-07922-y. Epub 2024 Sep 18. Nature. 2024. PMID: 39294371 Free PMC article.
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Pereira BA, Ritchie S, Chambers CR, Gordon KA, Magenau A, Murphy KJ, Nobis M, Tyma VM, Liew YF, Lucas MC, Naeini MM, Barkauskas DS, Chacon-Fajardo D, Howell AE, Parker AL, Warren SC, Reed DA, Lee V, Metcalf XL, Lee YK, O'Regan LP, Zhu J, Trpceski M, Fontaine ARM, Stoehr J, Rouet R, Lin X, Chitty JL, Porazinski S, Wu SZ, Filipe EC, Cadell AL, Holliday H, Yang J, Papanicolaou M, Lyons RJ, Zaratzian A, Tayao M, Da Silva A, Vennin C, Yin J, Dew AB, McMillan PJ, Goldstein LD, Deveson IW, Croucher DR, Samuel MS, Sim HW, Batten M, Chantrill L, Grimmond SM, Gill AJ, Samra J, Jeffry Evans TR, Sasaki T, Phan TG, Swarbrick A, Sansom OJ, Morton JP; Australian Pancreatic Cancer Matrix Atlas (APMA); Australian Pancreatic Cancer Genome Initiative (APGI); Pajic M, Parker BL, Herrmann D, Cox TR, Timpson P. Pereira BA, et al. Among authors: parker bl. Sci Adv. 2024 Jul 5;10(27):eadl1197. doi: 10.1126/sciadv.adl1197. Epub 2024 Jul 3. Sci Adv. 2024. PMID: 38959305 Free PMC article.
218 results