Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA.
Lei J, Qi R, Tang Y, Wang W, Wei G, Nussinov R, Ma B.
Lei J, et al. Among authors: qi r.
FASEB J. 2019 Mar;33(3):4225-4235. doi: 10.1096/fj.201801973R. Epub 2018 Dec 12.
FASEB J. 2019.
PMID: 30540922
Free PMC article.
This study provides physicochemical insight into delta133p53beta, delta133p53beta-DNA complexes, delta133p53beta's pathologic mechanism, and peptide-based inhibitor design against p53-related cancers.-Lei, J., Qi, R., Tang, Y., Wang, W., Wei, G., Nussinov, R. …
This study provides physicochemical insight into delta133p53beta, delta133p53beta-DNA complexes, delta133p53beta's pathologic mechanism, and …