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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.
Soroosh P, Wu J, Xue X, Song J, Sutton SW, Sablad M, Yu J, Nelen MI, Liu X, Castro G, Luna R, Crawford S, Banie H, Dandridge RA, Deng X, Bittner A, Kuei C, Tootoonchi M, Rozenkrants N, Herman K, Gao J, Yang XV, Sachen K, Ngo K, Fung-Leung WP, Nguyen S, de Leon-Tabaldo A, Blevitt J, Zhang Y, Cummings MD, Rao T, Mani NS, Liu C, McKinnon M, Milla ME, Fourie AM, Sun S. Soroosh P, et al. Among authors: song j. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12163-8. doi: 10.1073/pnas.1322807111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092323 Free PMC article.
The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomized, double-blind, placebo-controlled trial.
Ritchlin CT, Coates LC, Mease PJ, van der Heijde D, Song J, Jiang Y, Shawi M, Kollmeier AP, Rahman P. Ritchlin CT, et al. Among authors: song j. Trials. 2023 Jan 10;24(1):22. doi: 10.1186/s13063-022-06945-y. Trials. 2023. PMID: 36627711 Free PMC article.
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