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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
Eccles W, Blevitt JM, Booker JN, Chrovian CC, Crawford S, de Leon AR, Deng X, Fourie AM, Grice CA, Herman K, Karlsson L, Kearney AM, Lee-Dutra A, Liang J, Luna R, Pippel D, Rao N, Riley JP, Santillán A, Savall B, Tanis VM, Xue X, Young AL. Eccles W, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):811-5. doi: 10.1016/j.bmcl.2012.11.074. Epub 2012 Dec 5. Bioorg Med Chem Lett. 2013. PMID: 23260350
Phenotypic Approaches to Identify Inhibitors of B Cell Activation.
Rex EB, Kim S, Wiener J, Rao NL, Milla ME, DiSepio D. Rex EB, et al. Among authors: rao nl. J Biomol Screen. 2015 Aug;20(7):876-86. doi: 10.1177/1087057115585724. Epub 2015 May 6. J Biomol Screen. 2015. PMID: 25948491 Free PMC article.
A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.
Blevitt JM, Hack MD, Herman K, Chang L, Keith JM, Mirzadegan T, Rao NL, Lebsack AD, Milla ME. Blevitt JM, et al. Among authors: rao nl. J Biol Chem. 2016 Jun 10;291(24):12724-12731. doi: 10.1074/jbc.M116.725325. Epub 2016 Apr 16. J Biol Chem. 2016. PMID: 27129215 Free PMC article.
Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.
Tichenor MS, Wiener JJM, Rao NL, Pooley Deckhut C, Barbay JK, Kreutter KD, Bacani GM, Wei J, Chang L, Murrey HE, Wang W, Ahn K, Huber M, Rex E, Coe KJ, Wu J, Seierstad M, Bembenek SD, Leonard KA, Lebsack AD, Venable JD, Edwards JP. Tichenor MS, et al. Among authors: rao nl. ACS Med Chem Lett. 2021 Apr 5;12(5):782-790. doi: 10.1021/acsmedchemlett.1c00044. eCollection 2021 May 13. ACS Med Chem Lett. 2021. PMID: 34055226 Free PMC article.
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Tichenor MS, Wiener JJM, Rao NL, Bacani GM, Wei J, Pooley Deckhut C, Barbay JK, Kreutter KD, Chang L, Clancy KW, Murrey HE, Wang W, Ahn K, Huber M, Rex E, Coe KJ, Wu J, Rui H, Sepassi K, Gaudiano M, Bekkers M, Cornelissen I, Packman K, Seierstad M, Xiouras C, Bembenek SD, Alexander R, Milligan C, Balasubramanian S, Lebsack AD, Venable JD, Philippar U, Edwards JP, Hirst G. Tichenor MS, et al. Among authors: rao nl. J Med Chem. 2022 Nov 10;65(21):14326-14336. doi: 10.1021/acs.jmedchem.2c01026. Epub 2022 Oct 31. J Med Chem. 2022. PMID: 36314537
IRAK1: a critical signaling mediator of innate immunity.
Gottipati S, Rao NL, Fung-Leung WP. Gottipati S, et al. Among authors: rao nl. Cell Signal. 2008 Feb;20(2):269-76. doi: 10.1016/j.cellsig.2007.08.009. Epub 2007 Aug 23. Cell Signal. 2008. PMID: 17890055 Review.
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