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Cognitive deficits develop 1month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge.
Muccigrosso MM, Ford J, Benner B, Moussa D, Burnsides C, Fenn AM, Popovich PG, Lifshitz J, Walker FR, Eiferman DS, Godbout JP. Muccigrosso MM, et al. Among authors: eiferman ds. Brain Behav Immun. 2016 May;54:95-109. doi: 10.1016/j.bbi.2016.01.009. Epub 2016 Jan 14. Brain Behav Immun. 2016. PMID: 26774527 Free PMC article.
Traumatic brain injury-induced neuronal damage in the somatosensory cortex causes formation of rod-shaped microglia that promote astrogliosis and persistent neuroinflammation.
Witcher KG, Bray CE, Dziabis JE, McKim DB, Benner BN, Rowe RK, Kokiko-Cochran ON, Popovich PG, Lifshitz J, Eiferman DS, Godbout JP. Witcher KG, et al. Among authors: eiferman ds. Glia. 2018 Dec;66(12):2719-2736. doi: 10.1002/glia.23523. Epub 2018 Oct 30. Glia. 2018. PMID: 30378170 Free PMC article.
Traumatic Brain Injury Causes Chronic Cortical Inflammation and Neuronal Dysfunction Mediated by Microglia.
Witcher KG, Bray CE, Chunchai T, Zhao F, O'Neil SM, Gordillo AJ, Campbell WA, McKim DB, Liu X, Dziabis JE, Quan N, Eiferman DS, Fischer AJ, Kokiko-Cochran ON, Askwith C, Godbout JP. Witcher KG, et al. Among authors: eiferman ds. J Neurosci. 2021 Feb 17;41(7):1597-1616. doi: 10.1523/JNEUROSCI.2469-20.2020. Epub 2021 Jan 15. J Neurosci. 2021. PMID: 33452227 Free PMC article.
Pre-injury polypharmacy as a predictor of outcomes in trauma patients.
Evans DC, Gerlach AT, Christy JM, Jarvis AM, Lindsey DE, Whitmill ML, Eiferman D, Murphy CV, Cook CH, Beery PR 2nd, Steinberg SM, Stawicki SP. Evans DC, et al. Int J Crit Illn Inj Sci. 2011 Jul;1(2):104-9. doi: 10.4103/2229-5151.84793. Int J Crit Illn Inj Sci. 2011. PMID: 22229132 Free PMC article.
53 results