Capel RA - Search Results

1

Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart.

Capel RA, Bolton EL, Lin WK, Aston D, Wang Y, Liu W, Wang X, Burton RA, Bloor-Young D, Shade KT, Ruas M, Parrington J, Churchill GC, Lei M, Galione A, Terrar DA. Capel RA, et al. J Biol Chem. 2015 Dec 11;290(50):30087-98. doi: 10.1074/jbc.M115.684076. Epub 2015 Oct 5. J Biol Chem. 2015. PMID: 26438825 Free PMC article.

2

Cytosolic calcium ions exert a major influence on the firing rate and maintenance of pacemaker activity in guinea-pig sinus node.

Capel RA, Terrar DA. Capel RA, et al. Front Physiol. 2015 Feb 10;6:23. doi: 10.3389/fphys.2015.00023. eCollection 2015. Front Physiol. 2015. PMID: 25713538 Free PMC article.

3

The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat.

Capel RA, Terrar DA. Capel RA, et al. Front Physiol. 2015 Mar 25;6:80. doi: 10.3389/fphys.2015.00080. eCollection 2015. Front Physiol. 2015. PMID: 25859219 Free PMC article. Review.

4

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential.

Capel RA, Herring N, Kalla M, Yavari A, Mirams GR, Douglas G, Bub G, Channon K, Paterson DJ, Terrar DA, Burton RA. Capel RA, et al. Heart Rhythm. 2015 Oct;12(10):2186-94. doi: 10.1016/j.hrthm.2015.05.027. Epub 2015 May 27. Heart Rhythm. 2015. PMID: 26025323 Free PMC article.

5

Mapping cardiac microstructure of rabbit heart in different mechanical states by high resolution diffusion tensor imaging: A proof-of-principle study.

Teh I, Burton RA, McClymont D, Capel RA, Aston D, Kohl P, Schneider JE. Teh I, et al. Among authors: capel ra. Prog Biophys Mol Biol. 2016 Jul;121(2):85-96. doi: 10.1016/j.pbiomolbio.2016.06.001. Epub 2016 Jun 16. Prog Biophys Mol Biol. 2016. PMID: 27320383 Free PMC article.

6

Effect of sphingosine-1-phosphate on L-type calcium current and Ca(2+) transient in rat ventricular myocytes.

Egom EE, Bae JS, Capel R, Richards M, Ke Y, Pharithi RB, Maher V, Kruzliak P, Lei M. Egom EE, et al. Mol Cell Biochem. 2016 Aug;419(1-2):83-92. doi: 10.1007/s11010-016-2752-8. Epub 2016 Jul 2. Mol Cell Biochem. 2016. PMID: 27372350

7

High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.

Aston D, Capel RA, Ford KL, Christian HC, Mirams GR, Rog-Zielinska EA, Kohl P, Galione A, Burton RA, Terrar DA. Aston D, et al. Among authors: capel ra. Sci Rep. 2017 Jan 17;7:40620. doi: 10.1038/srep40620. Sci Rep. 2017. PMID: 28094777 Free PMC article.

8

Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca²⁺ transients in murine heart.

Wen Q, Gandhi K, Capel RA, Hao G, O'Shea C, Neagu G, Pearcey S, Pavlovic D, Terrar DA, Wu J, Faggian G, Camelliti P, Lei M. Wen Q, et al. Among authors: capel ra. J Physiol. 2018 Sep;596(17):3951-3965. doi: 10.1113/JP276239. Epub 2018 Jul 26. J Physiol. 2018. PMID: 29928770 Free PMC article.

9

IP₃-mediated Ca²⁺ release regulates atrial Ca²⁺ transients and pacemaker function by stimulation of adenylyl cyclases.

Capel RA, Bose SJ, Collins TP, Rajasundaram S, Ayagama T, Zaccolo M, Burton RB, Terrar DA. Capel RA, et al. Am J Physiol Heart Circ Physiol. 2021 Jan 1;320(1):H95-H107. doi: 10.1152/ajpheart.00380.2020. Epub 2020 Oct 16. Am J Physiol Heart Circ Physiol. 2021. PMID: 33064562 Free PMC article.

10

A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue.

Ayagama T, Bose SJ, Capel RA, Priestman DA, Berridge G, Fischer R, Galione A, Platt FM, Kramer H, Burton RAB. Ayagama T, et al. Among authors: capel ra. iScience. 2021 Aug 4;24(9):102949. doi: 10.1016/j.isci.2021.102949. eCollection 2021 Sep 24. iScience. 2021. PMID: 34466782 Free PMC article.

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