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A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit.

Wang J, Kuryatov A, Jin Z, Norleans J, Kamenecka TM, Kenny PJ, Lindstrom J. Wang J, et al. Among authors: norleans j. J Biol Chem. 2015 Nov 27;290(48):28834-46. doi: 10.1074/jbc.M115.676551. Epub 2015 Oct 2. J Biol Chem. 2015. PMID: 26432642 Free PMC article.

Discovery of an intrasubunit nicotinic acetylcholine receptor-binding site for the positive allosteric modulator Br-PBTC.

Norleans J, Wang J, Kuryatov A, Leffler A, Doebelin C, Kamenecka TM, Lindstrom J. Norleans J, et al. J Biol Chem. 2019 Aug 9;294(32):12132-12145. doi: 10.1074/jbc.RA118.006253. Epub 2019 Jun 20. J Biol Chem. 2019. PMID: 31221718 Free PMC article.

Selective lysis of breast carcinomas by simultaneous stimulation of sodium channels and blockade of sodium pumps.

Gould HJ 3rd, Norleans J, Ward TD, Reid C, Paul D. Gould HJ 3rd, et al. Among authors: norleans j. Oncotarget. 2018 Feb 26;9(21):15606-15615. doi: 10.18632/oncotarget.24581. eCollection 2018 Mar 20. Oncotarget. 2018. PMID: 29643996 Free PMC article.

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