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Page 1
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.
Sather BD, Romano Ibarra GS, Sommer K, Curinga G, Hale M, Khan IF, Singh S, Song Y, Gwiazda K, Sahni J, Jarjour J, Astrakhan A, Wagner TA, Scharenberg AM, Rawlings DJ. Sather BD, et al. Among authors: romano ibarra gs. Sci Transl Med. 2015 Sep 30;7(307):307ra156. doi: 10.1126/scitranslmed.aac5530. Sci Transl Med. 2015. PMID: 26424571 Free PMC article.
Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells.
Hale M, Mesojednik T, Romano Ibarra GS, Sahni J, Bernard A, Sommer K, Scharenberg AM, Rawlings DJ, Wagner TA. Hale M, et al. Among authors: romano ibarra gs. Mol Ther. 2017 Mar 1;25(3):570-579. doi: 10.1016/j.ymthe.2016.12.023. Epub 2017 Jan 28. Mol Ther. 2017. PMID: 28143740 Free PMC article.
Detargeting Lentiviral-Mediated CFTR Expression in Airway Basal Cells Using miR-106b.
Choi SH, Reeves RE, Romano Ibarra GS, Lynch TJ, Shahin WS, Feng Z, Gasser GN, Winter MC, Evans TIA, Liu X, Luo M, Zhang Y, Stoltz DA, Devor EJ, Yan Z, Engelhardt JF. Choi SH, et al. Among authors: romano ibarra gs. Genes (Basel). 2020 Oct 6;11(10):1169. doi: 10.3390/genes11101169. Genes (Basel). 2020. PMID: 33036232 Free PMC article.
A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis.
Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. Thurman AL, et al. Among authors: romano ibarra gs. Am J Respir Cell Mol Biol. 2022 Jun;66(6):612-622. doi: 10.1165/rcmb.2021-0499OC. Am J Respir Cell Mol Biol. 2022. PMID: 35235762 Free PMC article.
Lack of airway submucosal glands impairs respiratory host defenses.
Ostedgaard LS, Price MP, Whitworth KM, Abou Alaiwa MH, Fischer AJ, Warrier A, Samuel M, Spate LD, Allen PD, Hilkin BM, Romano Ibarra GS, Ortiz Bezara ME, Goodell BJ, Mather SE, Powers LS, Stroik MR, Gansemer ND, Hippee CE, Zarei K, Goeken JA, Businga TR, Hoffman EA, Meyerholz DK, Prather RS, Stoltz DA, Welsh MJ. Ostedgaard LS, et al. Among authors: romano ibarra gs. Elife. 2020 Oct 7;9:e59653. doi: 10.7554/eLife.59653. Elife. 2020. PMID: 33026343 Free PMC article.
TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin.
Rehman T, Thornell IM, Pezzulo AA, Thurman AL, Romano Ibarra GS, Karp PH, Tan P, Duffey ME, Welsh MJ. Rehman T, et al. Among authors: romano ibarra gs. Am J Physiol Cell Physiol. 2020 Aug 1;319(2):C331-C344. doi: 10.1152/ajpcell.00112.2020. Epub 2020 May 20. Am J Physiol Cell Physiol. 2020. PMID: 32432926 Free PMC article.
CFTR-rich ionocytes mediate chloride absorption across airway epithelia.
Lei L, Traore S, Romano Ibarra GS, Karp PH, Rehman T, Meyerholz DK, Zabner J, Stoltz DA, Sinn PL, Welsh MJ, McCray PB Jr, Thornell IM. Lei L, et al. Among authors: romano ibarra gs. J Clin Invest. 2023 Oct 16;133(20):e171268. doi: 10.1172/JCI171268. J Clin Invest. 2023. PMID: 37581935 Free PMC article.