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High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
Maesako M, Uemura M, Tashiro Y, Sasaki K, Watanabe K, Noda Y, Ueda K, Asada-Utsugi M, Kubota M, Okawa K, Ihara M, Shimohama S, Uemura K, Kinoshita A. Maesako M, et al. PLoS One. 2015 Sep 28;10(9):e0131199. doi: 10.1371/journal.pone.0131199. eCollection 2015. PLoS One. 2015. PMID: 26414661 Free PMC article.
Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes.
Devkota S, Zhou R, Nagarajan V, Maesako M, Do H, Noorani A, Overmeyer C, Bhattarai S, Douglas JT, Saraf A, Miao Y, Ackley BD, Shi Y, Wolfe MS. Devkota S, et al. Among authors: maesako m. Cell Rep. 2024 Feb 27;43(2):113761. doi: 10.1016/j.celrep.2024.113761. Epub 2024 Feb 13. Cell Rep. 2024. PMID: 38349793 Free PMC article.
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.
Zoltowska KM, Das U, Lismont S, Enzlein T, Maesako M, Houser MC, Franco ML, Özcan B, Moreira DG, Karachentsev D, Becker A, Hopf C, Vilar M, Berezovska O, Mobley W, Chávez-Gutiérrez L. Zoltowska KM, et al. Among authors: maesako m. bioRxiv [Preprint]. 2024 Apr 23:2023.08.02.551596. doi: 10.1101/2023.08.02.551596. bioRxiv. 2024. Update in: Elife. 2024 Jul 19;12:RP90690. doi: 10.7554/eLife.90690 PMID: 37577527 Free PMC article. Updated. Preprint.
Insulin regulates Presenilin 1 localization via PI3K/Akt signaling.
Maesako M, Uemura K, Kubota M, Ando K, Kuzuya A, Asada M, Kihara T, Kinoshita A. Maesako M, et al. Neurosci Lett. 2010 Oct 15;483(3):157-61. doi: 10.1016/j.neulet.2010.07.055. Epub 2010 Aug 7. Neurosci Lett. 2010. PMID: 20696212 Free article.
N-cadherin regulates p38 MAPK signaling via association with JNK-associated leucine zipper protein: implications for neurodegeneration in Alzheimer disease.
Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M, Aoyagi N, Yoshioka K, Okawa K, Inoue H, Kawamata J, Shimohama S, Arai T, Takahashi R, Kinoshita A. Ando K, et al. Among authors: maesako m. J Biol Chem. 2011 Mar 4;286(9):7619-28. doi: 10.1074/jbc.M110.158477. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177868 Free PMC article.
N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production.
Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A. Asada-Utsugi M, et al. Among authors: maesako m. J Neurochem. 2011 Oct;119(2):354-63. doi: 10.1111/j.1471-4159.2011.07364.x. Epub 2011 Sep 20. J Neurochem. 2011. PMID: 21699541 Free PMC article.
51 results