Wang Y - Search Results

1

CDK7-dependent transcriptional addiction in triple-negative breast cancer.

Wang Y, Zhang T, Kwiatkowski N, Abraham BJ, Lee TI, Xie S, Yuzugullu H, Von T, Li H, Lin Z, Stover DG, Lim E, Wang ZC, Iglehart JD, Young RA, Gray NS, Zhao JJ. Wang Y, et al. Among authors: wang zc. Cell. 2015 Sep 24;163(1):174-86. doi: 10.1016/j.cell.2015.08.063. Cell. 2015. PMID: 26406377 Free PMC article.

2

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Wang Y, Lee YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ. Wang Y, et al. Elife. 2014 May 20;3:e01763. doi: 10.7554/eLife.01763. Elife. 2014. PMID: 24844244 Free PMC article.

3

Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.

Wang Y, Begley M, Li Q, Huang HT, Lako A, Eck MJ, Gray NS, Mitchison TJ, Cantley LC, Zhao JJ. Wang Y, et al. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9810-5. doi: 10.1073/pnas.1606862113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528663 Free PMC article.

4

MELK is not necessary for the proliferation of basal-like breast cancer cells.

Huang HT, Seo HS, Zhang T, Wang Y, Jiang B, Li Q, Buckley DL, Nabet B, Roberts JM, Paulk J, Dastjerdi S, Winter GE, McLauchlan H, Moran J, Bradner JE, Eck MJ, Dhe-Paganon S, Zhao JJ, Gray NS. Huang HT, et al. Among authors: wang y. Elife. 2017 Sep 19;6:e26693. doi: 10.7554/eLife.26693. Elife. 2017. PMID: 28926338 Free PMC article.

5

Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Wang Y, Li YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao JJ. Wang Y, et al. Elife. 2018 Mar 12;7:e36414. doi: 10.7554/eLife.36414. Elife. 2018. PMID: 29528283 Free PMC article. No abstract available.

6

A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells.

Wang Y, Li BB, Li J, Roberts TM, Zhao JJ. Wang Y, et al. iScience. 2018 Nov 30;9:149-160. doi: 10.1016/j.isci.2018.10.015. Epub 2018 Oct 18. iScience. 2018. PMID: 30391850 Free PMC article.

7

Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers.

Sun B, Mason S, Wilson RC, Hazard SE, Wang Y, Fang R, Wang Q, Yeh ES, Yang M, Roberts TM, Zhao JJ, Wang Q. Sun B, et al. Among authors: wang y, wang q. Oncogene. 2020 Jan;39(1):50-63. doi: 10.1038/s41388-019-0953-9. Epub 2019 Aug 28. Oncogene. 2020. PMID: 31462705 Free PMC article.

8

Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion.

Zarei M, Du H, Nassar AH, Yan RE, Giannikou K, Johnson SH, Lam HC, Henske EP, Wang Y, Zhang T, Asara J, Kwiatkowski DJ. Zarei M, et al. Among authors: wang y. J Exp Med. 2019 Nov 4;216(11):2635-2652. doi: 10.1084/jem.20190251. Epub 2019 Sep 10. J Exp Med. 2019. PMID: 31506280 Free PMC article.

9

The Mediator captures CDK7, an attractive transcriptional target in cancer.

Wang Y, Manokaran C, Wu S, Roberts TM. Wang Y, et al. Cancer Cell. 2021 Sep 13;39(9):1184-1186. doi: 10.1016/j.ccell.2021.07.021. Epub 2021 Aug 19. Cancer Cell. 2021. PMID: 34416166 Free article.

10

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer.

Gao X, Wang Y, Ribeiro CF, Manokaran C, Chang H, Von T, Rodrigues S, Cizmecioglu O, Jia S, Korpal M, Korn JM, Wang Z, Schmit F, Jiang L, Pagliarini R, Yang Y, Sethi I, Signoretti S, Yuan GC, Loda M, Zhao JJ, Roberts TM. Gao X, et al. Among authors: wang z, wang y. Mol Cancer Res. 2022 May 4;20(5):673-685. doi: 10.1158/1541-7786.MCR-21-0322. Mol Cancer Res. 2022. PMID: 35105671 Free PMC article.

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