Hedley SJ - Search Results

1

Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.

Wurz RP, Pettus LH, Ashton K, Brown J, Chen JJ, Herberich B, Hong FT, Hu-Harrington E, Nguyen T, St Jean DJ Jr, Tadesse S, Bauer D, Kubryk M, Zhan J, Cooke K, Mitchell P, Andrews KL, Hsieh F, Hickman D, Kalyanaraman N, Wu T, Reid DL, Lobenhofer EK, Andrews DA, Everds N, Guzman R, Parsons AT, Hedley SJ, Tedrow J, Thiel OR, Potter M, Radinsky R, Beltran PJ, Tasker AS. Wurz RP, et al. Among authors: hedley sj. ACS Med Chem Lett. 2015 Jul 27;6(9):987-92. doi: 10.1021/acsmedchemlett.5b00193. eCollection 2015 Sep 10. ACS Med Chem Lett. 2015. PMID: 26396685 Free PMC article.

2

Development of a [3+3] cycloaddition strategy toward functionalized piperidines.

Hedley SJ, Moran WJ, Price DA, Harrity JP. Hedley SJ, et al. J Org Chem. 2003 May 30;68(11):4286-92. doi: 10.1021/jo030002c. J Org Chem. 2003. PMID: 12762728

3

Investigation into factors influencing stereoselectivity in the reactions of heterocycles with donor-acceptor-substituted rhodium carbenoids.

Hedley SJ, Ventura DL, Dominiak PM, Nygren CL, Davies HM. Hedley SJ, et al. J Org Chem. 2006 Jul 7;71(14):5349-56. doi: 10.1021/jo060779g. J Org Chem. 2006. PMID: 16808525

4

Asymmetric intermolecular C-H functionalization of benzyl silyl ethers mediated by chiral auxiliary-based aryldiazoacetates and chiral dirhodium catalysts.

Davies HM, Hedley SJ, Bohall BR. Davies HM, et al. Among authors: hedley sj. J Org Chem. 2005 Dec 23;70(26):10737-42. doi: 10.1021/jo051747g. J Org Chem. 2005. PMID: 16355994

5

Intermolecular reactions of electron-rich heterocycles with copper and rhodium carbenoids.

Davies HM, Hedley SJ. Davies HM, et al. Among authors: hedley sj. Chem Soc Rev. 2007 Jul;36(7):1109-19. doi: 10.1039/b607983k. Epub 2007 Feb 15. Chem Soc Rev. 2007. PMID: 17576478 Review.

6

Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.

Murthy V, Davies HM, Hedley SJ, Childers SR. Murthy V, et al. Among authors: hedley sj. Biochem Pharmacol. 2007 Jul 15;74(2):336-44. doi: 10.1016/j.bcp.2007.04.019. Epub 2007 Apr 27. Biochem Pharmacol. 2007. PMID: 17540345 Free PMC article.

7

Effective multiple oral administration of reverse genetics engineered infectious bursal disease virus in mice in the presence of neutralizing antibodies.

Hornyák Á, Lipinski KS, Bakonyi T, Forgách P, Horváth E, Farsang A, Hedley SJ, Palya V, Bakács T, Kovesdi I. Hornyák Á, et al. Among authors: hedley sj. J Gene Med. 2015 Jun-Jul;17(6-7):116-31. doi: 10.1002/jgm.2830. J Gene Med. 2015. PMID: 25929556

8

Adenoviral producer cells.

Kovesdi I, Hedley SJ. Kovesdi I, et al. Among authors: hedley sj. Viruses. 2010 Aug;2(8):1681-1703. doi: 10.3390/v2081681. Epub 2010 Aug 16. Viruses. 2010. PMID: 21994701 Free PMC article.

9

Targeted and shielded adenovectors for cancer therapy.

Hedley SJ, Chen J, Mountz JD, Li J, Curiel DT, Korokhov N, Kovesdi I. Hedley SJ, et al. Cancer Immunol Immunother. 2006 Nov;55(11):1412-9. doi: 10.1007/s00262-006-0158-2. Epub 2006 Apr 13. Cancer Immunol Immunother. 2006. PMID: 16612598 Free PMC article. Review.

10

Generation and selection of targeted adenoviruses embodying optimized vector properties.

Noureddini SC, Krendelshchikov A, Simonenko V, Hedley SJ, Douglas JT, Curiel DT, Korokhov N. Noureddini SC, et al. Among authors: hedley sj. Virus Res. 2006 Mar;116(1-2):185-95. doi: 10.1016/j.virusres.2005.10.002. Epub 2005 Nov 15. Virus Res. 2006. PMID: 16293334

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