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Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
Appleby TC, Greenstein AE, Hung M, Liclican A, Velasquez M, Villaseñor AG, Wang R, Wong MH, Liu X, Papalia GA, Schultz BE, Sakowicz R, Smith V, Kwon HJ. Appleby TC, et al. Among authors: greenstein ae. J Biol Chem. 2017 Apr 21;292(16):6810-6820. doi: 10.1074/jbc.M116.760579. Epub 2017 Feb 24. J Biol Chem. 2017. PMID: 28235803 Free PMC article.
MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors.
Juric V, O'Sullivan C, Stefanutti E, Kovalenko M, Greenstein A, Barry-Hamilton V, Mikaelian I, Degenhardt J, Yue P, Smith V, Mikels-Vigdal A. Juric V, et al. Among authors: greenstein a. PLoS One. 2018 Nov 30;13(11):e0207255. doi: 10.1371/journal.pone.0207255. eCollection 2018. PLoS One. 2018. PMID: 30500835 Free PMC article.
Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice.
Liu SB, Ikenaga N, Peng ZW, Sverdlov DY, Greenstein A, Smith V, Schuppan D, Popov Y. Liu SB, et al. Among authors: greenstein a. FASEB J. 2016 Apr;30(4):1599-609. doi: 10.1096/fj.14-268425. Epub 2015 Dec 23. FASEB J. 2016. PMID: 26700732
Fibrotic matrix stability was directly assessed using a stepwise collagen extraction assay and fibrotic septae morphometry. Liver cells and fibrosis were studied by histologic, biochemical methods and quantitative real-time reverse-transcription PCR. ...B., Ikenaga, N., Pe …
Fibrotic matrix stability was directly assessed using a stepwise collagen extraction assay and fibrotic septae morphometry. Liver cel …
456 results