Ghanam RH - Search Results

1

Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt.

Agamasu C, Ghanam RH, Saad JS. Agamasu C, et al. Among authors: ghanam rh. J Biol Chem. 2015 Nov 6;290(45):27403-27413. doi: 10.1074/jbc.M115.673939. Epub 2015 Sep 21. J Biol Chem. 2015. PMID: 26391397 Free PMC article.

2

Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.

Saad JS, Miller J, Tai J, Kim A, Ghanam RH, Summers MF. Saad JS, et al. Among authors: ghanam rh. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11364-9. doi: 10.1073/pnas.0602818103. Epub 2006 Jul 13. Proc Natl Acad Sci U S A. 2006. PMID: 16840558 Free PMC article.

3

Mutations that mimic phosphorylation of the HIV-1 matrix protein do not perturb the myristyl switch.

Saad JS, Kim A, Ghanam RH, Dalton AK, Vogt VM, Wu Z, Lu W, Summers MF. Saad JS, et al. Among authors: ghanam rh. Protein Sci. 2007 Aug;16(8):1793-7. doi: 10.1110/ps.072987607. Protein Sci. 2007. PMID: 17656588 Free PMC article.

4

Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.

Saad JS, Ablan SD, Ghanam RH, Kim A, Andrews K, Nagashima K, Soheilian F, Freed EO, Summers MF. Saad JS, et al. Among authors: ghanam rh. J Mol Biol. 2008 Oct 3;382(2):434-47. doi: 10.1016/j.jmb.2008.07.027. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18657545 Free PMC article.

5

Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH.

Fledderman EL, Fujii K, Ghanam RH, Waki K, Prevelige PE, Freed EO, Saad JS. Fledderman EL, et al. Among authors: ghanam rh. Biochemistry. 2010 Nov 9;49(44):9551-62. doi: 10.1021/bi101245j. Biochemistry. 2010. PMID: 20886905 Free PMC article.

6

Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure.

Ghanam RH, Fernandez TF, Fledderman EL, Saad JS. Ghanam RH, et al. J Biol Chem. 2010 Dec 31;285(53):41911-20. doi: 10.1074/jbc.M110.179093. Epub 2010 Oct 18. J Biol Chem. 2010. PMID: 20956522 Free PMC article.

7

NMR, biophysical, and biochemical studies reveal the minimal Calmodulin binding domain of the HIV-1 matrix protein.

Samal AB, Ghanam RH, Fernandez TF, Monroe EB, Saad JS. Samal AB, et al. Among authors: ghanam rh. J Biol Chem. 2011 Sep 23;286(38):33533-43. doi: 10.1074/jbc.M111.273623. Epub 2011 Jul 28. J Biol Chem. 2011. PMID: 21799007 Free PMC article.

8

Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly.

Ghanam RH, Samal AB, Fernandez TF, Saad JS. Ghanam RH, et al. Front Microbiol. 2012 Feb 17;3:55. doi: 10.3389/fmicb.2012.00055. eCollection 2012. Front Microbiol. 2012. PMID: 22363329 Free PMC article.

9

The Interplay between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt.

Agamasu C, Ghanam RH, Xu F, Sun Y, Chen Y, Saad JS. Agamasu C, et al. Among authors: ghanam rh. J Biol Chem. 2017 Jan 6;292(1):251-263. doi: 10.1074/jbc.M116.752816. Epub 2016 Nov 21. J Biol Chem. 2017. PMID: 27872186 Free PMC article.

10

The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P₂-binding site that targets Gag to the cell periphery.

Watanabe SM, Medina GN, Eastep GN, Ghanam RH, Vlach J, Saad JS, Carter CA. Watanabe SM, et al. Among authors: ghanam rh. J Biol Chem. 2018 Dec 7;293(49):18841-18853. doi: 10.1074/jbc.RA118.003947. Epub 2018 Oct 11. J Biol Chem. 2018. PMID: 30309982 Free PMC article.

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