Huber W - Search Results

1

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry.

Franken H, Mathieson T, Childs D, Sweetman GM, Werner T, Tögel I, Doce C, Gade S, Bantscheff M, Drewes G, Reinhard FB, Huber W, Savitski MM. Franken H, et al. Among authors: huber w. Nat Protoc. 2015 Oct;10(10):1567-93. doi: 10.1038/nprot.2015.101. Epub 2015 Sep 17. Nat Protoc. 2015. PMID: 26379230

2

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor.

Anders S, McCarthy DJ, Chen Y, Okoniewski M, Smyth GK, Huber W, Robinson MD. Anders S, et al. Among authors: huber w. Nat Protoc. 2013 Sep;8(9):1765-86. doi: 10.1038/nprot.2013.099. Epub 2013 Aug 22. Nat Protoc. 2013. PMID: 23975260

3

Measuring genetic interactions in human cells by RNAi and imaging.

Laufer C, Fischer B, Huber W, Boutros M. Laufer C, et al. Among authors: huber w. Nat Protoc. 2014 Oct;9(10):2341-53. doi: 10.1038/nprot.2014.160. Epub 2014 Sep 11. Nat Protoc. 2014. PMID: 25211512

4

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.

Reinhard FB, Eberhard D, Werner T, Franken H, Childs D, Doce C, Savitski MF, Huber W, Bantscheff M, Savitski MM, Drewes G. Reinhard FB, et al. Among authors: huber w. Nat Methods. 2015 Dec;12(12):1129-31. doi: 10.1038/nmeth.3652. Epub 2015 Nov 2. Nat Methods. 2015. PMID: 26524241

5

Drug-perturbation-based stratification of blood cancer.

Dietrich S, Oleś M, Lu J, Sellner L, Anders S, Velten B, Wu B, Hüllein J, da Silva Liberio M, Walther T, Wagner L, Rabe S, Ghidelli-Disse S, Bantscheff M, Oleś AK, Słabicki M, Mock A, Oakes CC, Wang S, Oppermann S, Lukas M, Kim V, Sill M, Benner A, Jauch A, Sutton LA, Young E, Rosenquist R, Liu X, Jethwa A, Lee KS, Lewis J, Putzker K, Lutz C, Rossi D, Mokhir A, Oellerich T, Zirlik K, Herling M, Nguyen-Khac F, Plass C, Andersson E, Mustjoki S, von Kalle C, Ho AD, Hensel M, Dürig J, Ringshausen I, Zapatka M, Huber W, Zenz T. Dietrich S, et al. Among authors: huber w. J Clin Invest. 2018 Jan 2;128(1):427-445. doi: 10.1172/JCI93801. Epub 2017 Dec 11. J Clin Invest. 2018. PMID: 29227286 Free PMC article.

6

Proteome-wide identification of ubiquitin interactions using UbIA-MS.

Zhang X, Smits AH, van Tilburg GB, Ovaa H, Huber W, Vermeulen M. Zhang X, et al. Among authors: huber w. Nat Protoc. 2018 Mar;13(3):530-550. doi: 10.1038/nprot.2017.147. Epub 2018 Feb 15. Nat Protoc. 2018. PMID: 29446774

7

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

Jethwa A, Słabicki M, Hüllein J, Jentzsch M, Dalal V, Rabe S, Wagner L, Walther T, Klapper W; MMML Network Project; Bohnenberger H, Rettel M, Lu J, Smits AH, Stein F, Savitski MM, Huber W, Aylon Y, Oren M, Zenz T. Jethwa A, et al. Among authors: huber w. Blood. 2018 Jun 21;131(25):2789-2802. doi: 10.1182/blood-2017-09-806679. Epub 2018 Apr 13. Blood. 2018. PMID: 29653964 Free article.

8

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP.

Sridharan S, Kurzawa N, Werner T, Günthner I, Helm D, Huber W, Bantscheff M, Savitski MM. Sridharan S, et al. Among authors: huber w. Nat Commun. 2019 Mar 11;10(1):1155. doi: 10.1038/s41467-019-09107-y. Nat Commun. 2019. PMID: 30858367 Free PMC article.

9

Nonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins.

Childs D, Bach K, Franken H, Anders S, Kurzawa N, Bantscheff M, Savitski MM, Huber W. Childs D, et al. Among authors: huber w. Mol Cell Proteomics. 2019 Dec;18(12):2506-2515. doi: 10.1074/mcp.TIR119.001481. Epub 2019 Oct 3. Mol Cell Proteomics. 2019. PMID: 31582558 Free PMC article.

10

Biological plasticity rescues target activity in CRISPR knock outs.

Smits AH, Ziebell F, Joberty G, Zinn N, Mueller WF, Clauder-Münster S, Eberhard D, Fälth Savitski M, Grandi P, Jakob P, Michon AM, Sun H, Tessmer K, Bürckstümmer T, Bantscheff M, Steinmetz LM, Drewes G, Huber W. Smits AH, et al. Among authors: huber w. Nat Methods. 2019 Nov;16(11):1087-1093. doi: 10.1038/s41592-019-0614-5. Epub 2019 Oct 28. Nat Methods. 2019. PMID: 31659326

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