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The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological responses in vitro and in vivo.
Flynn AN, Tillu DV, Asiedu MN, Hoffman J, Vagner J, Price TJ, Boitano S. Flynn AN, et al. Among authors: vagner j. J Biol Chem. 2011 May 27;286(21):19076-88. doi: 10.1074/jbc.M110.185264. Epub 2011 Apr 5. J Biol Chem. 2011. PMID: 21467041 Free PMC article.
Potent agonists of the protease activated receptor 2 (PAR2).
Boitano S, Flynn AN, Schulz SM, Hoffman J, Price TJ, Vagner J. Boitano S, et al. Among authors: vagner j. J Med Chem. 2011 Mar 10;54(5):1308-13. doi: 10.1021/jm1013049. Epub 2011 Feb 4. J Med Chem. 2011. PMID: 21294569 Free PMC article.
107 results