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Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.
Molenaar RJ, Botman D, Smits MA, Hira VV, van Lith SA, Stap J, Henneman P, Khurshed M, Lenting K, Mul AN, Dimitrakopoulou D, van Drunen CM, Hoebe RA, Radivoyevitch T, Wilmink JW, Maciejewski JP, Vandertop WP, Leenders WP, Bleeker FE, van Noorden CJ. Molenaar RJ, et al. Among authors: van drunen cm, van lith sa, van noorden cj. Cancer Res. 2015 Nov 15;75(22):4790-802. doi: 10.1158/0008-5472.CAN-14-3603. Epub 2015 Sep 11. Cancer Res. 2015. PMID: 26363012
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
Navis AC, Niclou SP, Fack F, Stieber D, van Lith S, Verrijp K, Wright A, Stauber J, Tops B, Otte-Holler I, Wevers RA, van Rooij A, Pusch S, von Deimling A, Tigchelaar W, van Noorden CJ, Wesseling P, Leenders WP. Navis AC, et al. Acta Neuropathol Commun. 2013 May 29;1:18. doi: 10.1186/2051-5960-1-18. Acta Neuropathol Commun. 2013. PMID: 24252742 Free PMC article.
Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?
van Lith SA, Navis AC, Verrijp K, Niclou SP, Bjerkvig R, Wesseling P, Tops B, Molenaar R, van Noorden CJ, Leenders WP. van Lith SA, et al. Among authors: van noorden cj. Biochim Biophys Acta. 2014 Aug;1846(1):66-74. doi: 10.1016/j.bbcan.2014.04.004. Epub 2014 Apr 18. Biochim Biophys Acta. 2014. PMID: 24747768 Review.
Identification of a novel MET mutation in high-grade glioma resulting in an auto-active intracellular protein.
Navis AC, van Lith SA, van Duijnhoven SM, de Pooter M, Yetkin-Arik B, Wesseling P, Hendriks WJ, Venselaar H, Timmer M, van Cleef P, van Bergen En Henegouwen P, Best MG, Wurdinger TD, Tops BB, Leenders WP. Navis AC, et al. Among authors: van bergen en henegouwen p, van lith sa, van duijnhoven sm, van cleef p. Acta Neuropathol. 2015 Jul;130(1):131-44. doi: 10.1007/s00401-015-1420-5. Epub 2015 Apr 11. Acta Neuropathol. 2015. PMID: 25862637 Free PMC article.
Identification of a novel inactivating mutation in Isocitrate Dehydrogenase 1 (IDH1-R314C) in a high grade astrocytoma.
van Lith SA, Navis AC, Lenting K, Verrijp K, Schepens JT, Hendriks WJ, Schubert NA, Venselaar H, Wevers RA, van Rooij A, Wesseling P, Molenaar RJ, van Noorden CJ, Pusch S, Tops B, Leenders WP. van Lith SA, et al. Among authors: van rooij a, van noorden cj. Sci Rep. 2016 Jul 27;6:30486. doi: 10.1038/srep30486. Sci Rep. 2016. PMID: 27460417 Free PMC article.
In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued.
van Lith SA, Roodink I, Verhoeff JJ, Mäkinen PI, Lappalainen JP, Ylä-Herttuala S, Raats J, van Wijk E, Roepman R, Letteboer SJ, Verrijp K, Leenders WP. van Lith SA, et al. Among authors: van wijk e. Oncotarget. 2016 Nov 1;7(44):71594-71607. doi: 10.18632/oncotarget.12261. Oncotarget. 2016. PMID: 27689404 Free PMC article.
Targeting the extracellular matrix of ovarian cancer using functionalized, drug loaded lyophilisomes.
van der Steen SC, Raavé R, Langerak S, van Houdt L, van Duijnhoven SM, van Lith SA, Massuger LF, Daamen WF, Leenders WP, van Kuppevelt TH. van der Steen SC, et al. Among authors: van houdt l, van kuppevelt th, van duijnhoven sm, van lith sa. Eur J Pharm Biopharm. 2017 Apr;113:229-239. doi: 10.1016/j.ejpb.2016.12.010. Epub 2016 Dec 26. Eur J Pharm Biopharm. 2017. PMID: 28034806 Free article.
Self-Assembling VHH-Elastin-Like Peptides for Photodynamic Nanomedicine.
Pille J, van Lith SA, van Hest JC, Leenders WP. Pille J, et al. Among authors: van hest jc, van lith sa. Biomacromolecules. 2017 Apr 10;18(4):1302-1310. doi: 10.1021/acs.biomac.7b00064. Epub 2017 Mar 16. Biomacromolecules. 2017. PMID: 28269985 Free PMC article.
33 results