Brüning JC - Search Results

1

Hypothalamic UDP Increases in Obesity and Promotes Feeding via P2Y6-Dependent Activation of AgRP Neurons.

Steculorum SM, Paeger L, Bremser S, Evers N, Hinze Y, Idzko M, Kloppenburg P, Brüning JC. Steculorum SM, et al. Among authors: bruning jc. Cell. 2015 Sep 10;162(6):1404-17. doi: 10.1016/j.cell.2015.08.032. Cell. 2015. PMID: 26359991 Free article.

2

Agouti-related peptide-expressing neurons are mandatory for feeding.

Gropp E, Shanabrough M, Borok E, Xu AW, Janoschek R, Buch T, Plum L, Balthasar N, Hampel B, Waisman A, Barsh GS, Horvath TL, Brüning JC. Gropp E, et al. Among authors: bruning jc. Nat Neurosci. 2005 Oct;8(10):1289-91. doi: 10.1038/nn1548. Epub 2005 Sep 11. Nat Neurosci. 2005. PMID: 16158063

3

Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production.

Könner AC, Janoschek R, Plum L, Jordan SD, Rother E, Ma X, Xu C, Enriori P, Hampel B, Barsh GS, Kahn CR, Cowley MA, Ashcroft FM, Brüning JC. Könner AC, et al. Among authors: bruning jc. Cell Metab. 2007 Jun;5(6):438-49. doi: 10.1016/j.cmet.2007.05.004. Cell Metab. 2007. PMID: 17550779 Free article.

4

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.

Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC. Mesaros A, et al. Among authors: bruning jc. Cell Metab. 2008 Mar;7(3):236-48. doi: 10.1016/j.cmet.2008.01.007. Cell Metab. 2008. PMID: 18316029 Free article.

5

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.

Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC. Belgardt BF, et al. Among authors: bruning jc. Cell Metab. 2008 Apr;7(4):291-301. doi: 10.1016/j.cmet.2008.01.006. Cell Metab. 2008. PMID: 18396135 Free article.

6

Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.

Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT. Ernst MB, et al. Among authors: bruning jc. J Neurosci. 2009 Sep 16;29(37):11582-93. doi: 10.1523/JNEUROSCI.5712-08.2009. J Neurosci. 2009. PMID: 19759305 Free PMC article.

7

Hormone and glucose signalling in POMC and AgRP neurons.

Belgardt BF, Okamura T, Brüning JC. Belgardt BF, et al. Among authors: bruning jc. J Physiol. 2009 Nov 15;587(Pt 22):5305-14. doi: 10.1113/jphysiol.2009.179192. Epub 2009 Sep 21. J Physiol. 2009. PMID: 19770186 Free PMC article. Review.

8

MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity.

Kleinridders A, Schenten D, Könner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Brüning JC. Kleinridders A, et al. Among authors: bruning jc. Cell Metab. 2009 Oct;10(4):249-59. doi: 10.1016/j.cmet.2009.08.013. Cell Metab. 2009. PMID: 19808018 Free PMC article.

9

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.

Jordan SD, Krüger M, Willmes DM, Redemann N, Wunderlich FT, Brönneke HS, Merkwirth C, Kashkar H, Olkkonen VM, Böttger T, Braun T, Seibler J, Brüning JC. Jordan SD, et al. Among authors: bruning jc. Nat Cell Biol. 2011 Apr;13(4):434-46. doi: 10.1038/ncb2211. Epub 2011 Mar 27. Nat Cell Biol. 2011. PMID: 21441927

10

Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits.

Hult S, Soylu R, Björklund T, Belgardt BF, Mauer J, Brüning JC, Kirik D, Petersén Å. Hult S, et al. Among authors: bruning jc. Cell Metab. 2011 Apr 6;13(4):428-439. doi: 10.1016/j.cmet.2011.02.013. Cell Metab. 2011. PMID: 21459327 Free article.

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