Cars O - Search Results

1

A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants.

Khan DD, Lagerbäck P, Cao S, Lustig U, Nielsen EI, Cars O, Hughes D, Andersson DI, Friberg LE. Khan DD, et al. Among authors: cars o. J Antimicrob Chemother. 2015 Nov;70(11):3051-60. doi: 10.1093/jac/dkv233. Epub 2015 Sep 7. J Antimicrob Chemother. 2015. PMID: 26349518

2

Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on the skin of human volunteers.

Gustafsson I, Cars O, Andersson DI. Gustafsson I, et al. Among authors: cars o. J Antimicrob Chemother. 2003 Aug;52(2):258-63. doi: 10.1093/jac/dkg331. Epub 2003 Jul 15. J Antimicrob Chemother. 2003. PMID: 12865395

3

Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage.

Gustafsson I, Sjölund M, Torell E, Johannesson M, Engstrand L, Cars O, Andersson DI. Gustafsson I, et al. Among authors: cars o. J Antimicrob Chemother. 2003 Oct;52(4):645-50. doi: 10.1093/jac/dkg427. Epub 2003 Sep 12. J Antimicrob Chemother. 2003. PMID: 12972454

4

Mutant prevention concentrations of ciprofloxacin for urinary tract infection isolates of Escherichia coli.

Marcusson LL, Olofsson SK, Komp Lindgren P, Cars O, Hughes D. Marcusson LL, et al. Among authors: cars o. J Antimicrob Chemother. 2005 Jun;55(6):938-43. doi: 10.1093/jac/dki136. Epub 2005 Apr 28. J Antimicrob Chemother. 2005. PMID: 15860549

5

Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli.

Olofsson SK, Geli P, Andersson DI, Cars O. Olofsson SK, et al. Among authors: cars o. Antimicrob Agents Chemother. 2005 Dec;49(12):5081-91. doi: 10.1128/AAC.49.12.5081-5091.2005. Antimicrob Agents Chemother. 2005. PMID: 16304176 Free PMC article.

6

Selection of ciprofloxacin resistance in Escherichia coli in an in vitro kinetic model: relation between drug exposure and mutant prevention concentration.

Olofsson SK, Marcusson LL, Komp Lindgren P, Hughes D, Cars O. Olofsson SK, et al. Among authors: cars o. J Antimicrob Chemother. 2006 Jun;57(6):1116-21. doi: 10.1093/jac/dkl135. Epub 2006 Apr 19. J Antimicrob Chemother. 2006. PMID: 16624874

7

Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments.

Nielsen EI, Viberg A, Löwdin E, Cars O, Karlsson MO, Sandström M. Nielsen EI, et al. Among authors: cars o. Antimicrob Agents Chemother. 2007 Jan;51(1):128-36. doi: 10.1128/AAC.00604-06. Epub 2006 Oct 23. Antimicrob Agents Chemother. 2007. PMID: 17060524 Free PMC article.

8

Dose-related selection of fluoroquinolone-resistant Escherichia coli.

Olofsson SK, Marcusson LL, Strömbäck A, Hughes D, Cars O. Olofsson SK, et al. Among authors: cars o. J Antimicrob Chemother. 2007 Oct;60(4):795-801. doi: 10.1093/jac/dkm265. Epub 2007 Jul 16. J Antimicrob Chemother. 2007. PMID: 17635875

9

Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model.

Nielsen EI, Cars O, Friberg LE. Nielsen EI, et al. Among authors: cars o. Antimicrob Agents Chemother. 2011 Apr;55(4):1571-9. doi: 10.1128/AAC.01286-10. Epub 2011 Jan 31. Antimicrob Agents Chemother. 2011. PMID: 21282424 Free PMC article.

10

Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization.

Nielsen EI, Cars O, Friberg LE. Nielsen EI, et al. Among authors: cars o. Antimicrob Agents Chemother. 2011 Oct;55(10):4619-30. doi: 10.1128/AAC.00182-11. Epub 2011 Aug 1. Antimicrob Agents Chemother. 2011. PMID: 21807983 Free PMC article.

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