Fearns C - Search Results

1

Targeting protein aggregation for the treatment of degenerative diseases.

Eisele YS, Monteiro C, Fearns C, Encalada SE, Wiseman RL, Powers ET, Kelly JW. Eisele YS, et al. Among authors: fearns c. Nat Rev Drug Discov. 2015 Nov;14(11):759-80. doi: 10.1038/nrd4593. Epub 2015 Sep 4. Nat Rev Drug Discov. 2015. PMID: 26338154 Free PMC article. Review.

2

Current and future treatment of amyloid diseases.

Ankarcrona M, Winblad B, Monteiro C, Fearns C, Powers ET, Johansson J, Westermark GT, Presto J, Ericzon BG, Kelly JW. Ankarcrona M, et al. Among authors: fearns c. J Intern Med. 2016 Aug;280(2):177-202. doi: 10.1111/joim.12506. Epub 2016 May 10. J Intern Med. 2016. PMID: 27165517 Free PMC article. Review.

3

The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.

Johnson SM, Connelly S, Fearns C, Powers ET, Kelly JW. Johnson SM, et al. Among authors: fearns c. J Mol Biol. 2012 Aug 10;421(2-3):185-203. doi: 10.1016/j.jmb.2011.12.060. Epub 2012 Jan 5. J Mol Biol. 2012. PMID: 22244854 Free PMC article. Review.

4

A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.

Hayashi M, Imanaka-Yoshida K, Yoshida T, Wood M, Fearns C, Tatake RJ, Lee JD. Hayashi M, et al. Among authors: fearns c. Nat Med. 2006 Jan;12(1):128-32. doi: 10.1038/nm1327. Epub 2005 Dec 4. Nat Med. 2006. PMID: 16327803

5

Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling.

Zhu JH, Chen R, Yi W, Cantin GT, Fearns C, Yang Y, Yates JR 3rd, Lee JD. Zhu JH, et al. Among authors: fearns c. Oncogene. 2008 Apr 17;27(18):2525-31. doi: 10.1038/sj.onc.1210922. Epub 2007 Nov 5. Oncogene. 2008. PMID: 17982484

6

CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.

Chen RQ, Yang QK, Lu BW, Yi W, Cantin G, Chen YL, Fearns C, Yates JR 3rd, Lee JD. Chen RQ, et al. Among authors: fearns c. Cancer Res. 2009 Mar 15;69(6):2663-8. doi: 10.1158/0008-5472.CAN-08-3222. Epub 2009 Mar 10. Cancer Res. 2009. PMID: 19276368 Free PMC article.

7

Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein.

Yang Q, Deng X, Lu B, Cameron M, Fearns C, Patricelli MP, Yates JR 3rd, Gray NS, Lee JD. Yang Q, et al. Among authors: fearns c. Cancer Cell. 2010 Sep 14;18(3):258-67. doi: 10.1016/j.ccr.2010.08.008. Cancer Cell. 2010. PMID: 20832753 Free PMC article.

8

Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis.

Hayashi M, Fearns C, Eliceiri B, Yang Y, Lee JD. Hayashi M, et al. Among authors: fearns c. Cancer Res. 2005 Sep 1;65(17):7699-706. doi: 10.1158/0008-5472.CAN-04-4540. Cancer Res. 2005. PMID: 16140937

9

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest.

Wang X, McGowan CH, Zhao M, He L, Downey JS, Fearns C, Wang Y, Huang S, Han J. Wang X, et al. Among authors: fearns c. Mol Cell Biol. 2000 Jul;20(13):4543-52. doi: 10.1128/MCB.20.13.4543-4552.2000. Mol Cell Biol. 2000. PMID: 10848581 Free PMC article.

10

Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.

Lo JF, Hayashi M, Woo-Kim S, Tian B, Huang JF, Fearns C, Takayama S, Zapata JM, Yang Y, Lee JD. Lo JF, et al. Among authors: fearns c. Mol Cell Biol. 2004 Mar;24(6):2226-36. doi: 10.1128/MCB.24.6.2226-2236.2004. Mol Cell Biol. 2004. PMID: 14993262 Free PMC article.

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