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136 results

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Page 1
P2Y13 receptor regulates HDL metabolism and atherosclerosis in vivo.
Goffinet M, Tardy C, Boubekeur N, Cholez G, Bluteau A, Oniciu DC, Lalwani ND, Dasseux JL, Barbaras R, Baron R. Goffinet M, et al. Among authors: lalwani nd. PLoS One. 2014 Apr 25;9(4):e95807. doi: 10.1371/journal.pone.0095807. eCollection 2014. PLoS One. 2014. PMID: 24769858 Free PMC article.
CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice.
Tardy C, Goffinet M, Boubekeur N, Ackermann R, Sy G, Bluteau A, Cholez G, Keyserling C, Lalwani N, Paolini JF, Dasseux JL, Barbaras R, Baron R. Tardy C, et al. Among authors: lalwani n. Atherosclerosis. 2014 Jan;232(1):110-8. doi: 10.1016/j.atherosclerosis.2013.10.018. Epub 2013 Nov 8. Atherosclerosis. 2014. PMID: 24401224
HDL mimetic peptide CER-522 treatment regresses left ventricular diastolic dysfunction in cholesterol-fed rabbits.
Merlet N, Busseuil D, Mihalache-Avram T, Mecteau M, Shi Y, Nachar W, Brand G, Brodeur MR, Charpentier D, Rhainds D, Sy G, Schwendeman A, Lalwani N, Dasseux JL, Rhéaume E, Tardif JC. Merlet N, et al. Among authors: lalwani n. Int J Cardiol. 2016 Jul 15;215:364-71. doi: 10.1016/j.ijcard.2016.04.029. Epub 2016 Apr 12. Int J Cardiol. 2016. PMID: 27128563
Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids.
Oniciu DC, Dasseux JL, Yang J, Mueller R, Pop E, Denysenko A, Duan C, Huang TB, Zhang L, Krause BR, Drake SL, Lalwani N, Cramer CT, Goetz B, Pape ME, McKee A, Fici GJ, Lutostanski JM, Brown SC, Bisgaier CL. Oniciu DC, et al. Among authors: lalwani n. J Med Chem. 2006 Jan 12;49(1):334-48. doi: 10.1021/jm050650j. J Med Chem. 2006. PMID: 16392818
Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol.
Ray KK, Bays HE, Catapano AL, Lalwani ND, Bloedon LT, Sterling LR, Robinson PL, Ballantyne CM; CLEAR Harmony Trial. Ray KK, et al. N Engl J Med. 2019 Mar 14;380(11):1022-1032. doi: 10.1056/NEJMoa1803917. N Engl J Med. 2019. PMID: 30865796 Free article. Clinical Trial.
Complementary low-density lipoprotein-cholesterol lowering and pharmacokinetics of adding bempedoic acid (ETC-1002) to high-dose atorvastatin background therapy in hypercholesterolemic patients: A randomized placebo-controlled trial.
Lalwani ND, Hanselman JC, MacDougall DE, Sterling LR, Cramer CT. Lalwani ND, et al. J Clin Lipidol. 2019 Jul-Aug;13(4):568-579. doi: 10.1016/j.jacl.2019.05.003. Epub 2019 May 13. J Clin Lipidol. 2019. PMID: 31202641 Clinical Trial.
Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease: The CLEAR Wisdom Randomized Clinical Trial.
Goldberg AC, Leiter LA, Stroes ESG, Baum SJ, Hanselman JC, Bloedon LT, Lalwani ND, Patel PM, Zhao X, Duell PB. Goldberg AC, et al. JAMA. 2019 Nov 12;322(18):1780-1788. doi: 10.1001/jama.2019.16585. JAMA. 2019. PMID: 31714986 Free PMC article. Clinical Trial.
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