Melton DW - Search Results

1

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.

Chapman TM, Wallace C, Gillen KJ, Bakrania P, Khurana P, Coombs PJ, Fox S, Bureau EA, Brownlees J, Melton DW, Saxty B. Chapman TM, et al. Among authors: melton dw. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4104-8. doi: 10.1016/j.bmcl.2015.08.024. Epub 2015 Aug 14. Bioorg Med Chem Lett. 2015. PMID: 26321360

2

Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance.

McNeil EM, Astell KR, Ritchie AM, Shave S, Houston DR, Bakrania P, Jones HM, Khurana P, Wallace C, Chapman T, Wear MA, Walkinshaw MD, Saxty B, Melton DW. McNeil EM, et al. Among authors: melton dw. DNA Repair (Amst). 2015 Jul;31:19-28. doi: 10.1016/j.dnarep.2015.04.002. Epub 2015 Apr 22. DNA Repair (Amst). 2015. PMID: 25956741

3

Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.

Chapman TM, Gillen KJ, Wallace C, Lee MT, Bakrania P, Khurana P, Coombs PJ, Stennett L, Fox S, Bureau EA, Brownlees J, Melton DW, Saxty B. Chapman TM, et al. Among authors: melton dw. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4097-103. doi: 10.1016/j.bmcl.2015.08.031. Epub 2015 Aug 17. Bioorg Med Chem Lett. 2015. PMID: 26318993

4

DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy.

McNeil EM, Melton DW. McNeil EM, et al. Among authors: melton dw. Nucleic Acids Res. 2012 Nov 1;40(20):9990-10004. doi: 10.1093/nar/gks818. Epub 2012 Aug 31. Nucleic Acids Res. 2012. PMID: 22941649 Free PMC article. Review.

5

A novel transcript for DNA repair gene Ercc1 in mouse skin.

Song L, Winter AG, Selfridge J, Melton DW. Song L, et al. Among authors: melton dw. Transgenic Res. 2011 Feb;20(1):109-22. doi: 10.1007/s11248-010-9396-3. Epub 2010 Apr 21. Transgenic Res. 2011. PMID: 20407824

6

Characterization of premature liver polyploidy in DNA repair (Ercc1)-deficient mice.

Chipchase MD, O'Neill M, Melton DW. Chipchase MD, et al. Among authors: melton dw. Hepatology. 2003 Oct;38(4):958-66. doi: 10.1053/jhep.2003.50421. Hepatology. 2003. PMID: 14512883

7

Identification of DNA repair gene Ercc1 as a novel target in melanoma.

Song L, Ritchie AM, McNeil EM, Li W, Melton DW. Song L, et al. Among authors: melton dw. Pigment Cell Melanoma Res. 2011 Oct;24(5):966-71. doi: 10.1111/j.1755-148X.2011.00882.x. Epub 2011 Jul 28. Pigment Cell Melanoma Res. 2011. PMID: 21722328

8

The formation of UV-induced chromosome aberrations involves ERCC1 and XPF but not other nucleotide excision repair genes.

Chipchase MD, Melton DW. Chipchase MD, et al. Among authors: melton dw. DNA Repair (Amst). 2002 Apr 29;1(4):335-40. doi: 10.1016/s1568-7864(02)00010-1. DNA Repair (Amst). 2002. PMID: 12509251

9

Cisplatin regulates the MAPK kinase pathway to induce increased expression of DNA repair gene ERCC1 and increase melanoma chemoresistance.

Li W, Melton DW. Li W, et al. Among authors: melton dw. Oncogene. 2012 May 10;31(19):2412-22. doi: 10.1038/onc.2011.426. Epub 2011 Sep 26. Oncogene. 2012. PMID: 21996734

10

DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma.

Povey JE, Darakhshan F, Robertson K, Bisset Y, Mekky M, Rees J, Doherty V, Kavanagh G, Anderson N, Campbell H, MacKie RM, Melton DW. Povey JE, et al. Among authors: melton dw. Carcinogenesis. 2007 May;28(5):1087-93. doi: 10.1093/carcin/bgl257. Epub 2007 Jan 8. Carcinogenesis. 2007. PMID: 17210993

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