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NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.
Jayavelu AK, Müller JP, Bauer R, Böhmer SA, Lässig J, Cerny-Reiterer S, Sperr WR, Valent P, Maurer B, Moriggl R, Schröder K, Shah AM, Fischer M, Scholl S, Barth J, Oellerich T, Berg T, Serve H, Frey S, Fischer T, Heidel FH, Böhmer FD. Jayavelu AK, et al. Among authors: fischer t, fischer m. Leukemia. 2016 Feb;30(2):473-83. doi: 10.1038/leu.2015.234. Epub 2015 Aug 26. Leukemia. 2016. PMID: 26308771
A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling.
Caldarelli A, Müller JP, Paskowski-Rogacz M, Herrmann K, Bauer R, Koch S, Heninger AK, Krastev D, Ding L, Kasper S, Fischer T, Brodhun M, Böhmer FD, Buchholz F. Caldarelli A, et al. Among authors: fischer t. Leukemia. 2013 Dec;27(12):2301-10. doi: 10.1038/leu.2013.83. Epub 2013 Mar 19. Leukemia. 2013. PMID: 23508117 Free PMC article.
Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo.
Arreba-Tutusaus P, Mack TS, Bullinger L, Schnöder TM, Polanetzki A, Weinert S, Ballaschk A, Wang Z, Deshpande AJ, Armstrong SA, Döhner K, Fischer T, Heidel FH. Arreba-Tutusaus P, et al. Among authors: fischer t. Leukemia. 2016 May;30(5):1220-1225. doi: 10.1038/leu.2015.292. Epub 2015 Oct 21. Leukemia. 2016. PMID: 26487272 Free PMC article. No abstract available.
Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function.
Perner F, Schnöder TM, Ranjan S, Wolleschak D, Ebert C, Pils MC, Frey S, Polanetzki A, Fahldieck C, Schönborn U, Schraven B, Isermann B, Fischer T, Heidel FH. Perner F, et al. Among authors: fischer t. Leukemia. 2016 Apr;30(4):991-5. doi: 10.1038/leu.2015.218. Epub 2015 Aug 5. Leukemia. 2016. PMID: 26242463 No abstract available.
Gain of function in Jak2V617F-positive T-cells.
Nishanth G, Wolleschak D, Fahldieck C, Fischer T, Mullally A, Perner F, Schnöder TM, Just S, Heidel FH, Schlüter D. Nishanth G, et al. Among authors: fischer t. Leukemia. 2017 Apr;31(4):1000-1003. doi: 10.1038/leu.2017.6. Epub 2017 Jan 11. Leukemia. 2017. PMID: 28074070 No abstract available.
2,275 results