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Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action.
Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE Jr. Thomsen IP, et al. J Infect Dis. 2017 Apr 1;215(7):1124-1131. doi: 10.1093/infdis/jix071. J Infect Dis. 2017. PMID: 28186295 Free PMC article.
Genetic variation of staphylococcal LukAB toxin determines receptor tropism.
Perelman SS, James DBA, Boguslawski KM, Nelson CW, Ilmain JK, Zwack EE, Prescott RA, Mohamed A, Tam K, Chan R, Narechania A, Pawline MB, Vozhilla N, Moustafa AM, Kim SY, Dittmann M, Ekiert DC, Bhabha G, Shopsin B, Planet PJ, Koralov SB, Torres VJ. Perelman SS, et al. Among authors: james dba. Nat Microbiol. 2021 Jun;6(6):731-745. doi: 10.1038/s41564-021-00890-3. Epub 2021 Apr 19. Nat Microbiol. 2021. PMID: 33875847 Free PMC article.
The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.
Shewell LK, Harvey RM, Higgins MA, Day CJ, Hartley-Tassell LE, Chen AY, Gillen CM, James DB, Alonzo F 3rd, Torres VJ, Walker MJ, Paton AW, Paton JC, Jennings MP. Shewell LK, et al. Among authors: james db. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5312-20. doi: 10.1073/pnas.1412703111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422425 Free PMC article.
All major cholesterol-dependent cytolysins use glycans as cellular receptors.
Shewell LK, Day CJ, Jen FE, Haselhorst T, Atack JM, Reijneveld JF, Everest-Dass A, James DBA, Boguslawski KM, Brouwer S, Gillen CM, Luo Z, Kobe B, Nizet V, von Itzstein M, Walker MJ, Paton AW, Paton JC, Torres VJ, Jennings MP. Shewell LK, et al. Among authors: james dba. Sci Adv. 2020 May 22;6(21):eaaz4926. doi: 10.1126/sciadv.aaz4926. eCollection 2020 May. Sci Adv. 2020. PMID: 32494740 Free PMC article.
In Vitro Antimalarial Susceptibility of Plasmodium falciparum and Plasmodium berghei Isolates to Selected Antimalarial Agents, Column Chromatographic Subfractions of Glyphaea brevis Leaves Extract and FTIR and GCMS of SF8.
Anjuwon TM, Ehinmidu JO, Anigo KM, James DB. Anjuwon TM, et al. Among authors: james db. Trop Life Sci Res. 2023 Jun;34(2):279-297. doi: 10.21315/tlsr2023.34.2.14. Epub 2023 Jul 21. Trop Life Sci Res. 2023. PMID: 38144385 Free PMC article.
34 results