Hopwood JJ - Search Results

1

Butanolysis derivatization: improved sensitivity in LC-MS/MS quantitation of heparan sulfate in urine from mucopolysaccharidosis patients.

Trim PJ, Hopwood JJ, Snel MF. Trim PJ, et al. Among authors: hopwood jj. Anal Chem. 2015 Sep 15;87(18):9243-50. doi: 10.1021/acs.analchem.5b01743. Epub 2015 Aug 27. Anal Chem. 2015. PMID: 26301744

2

A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA.

Trim PJ, Lau AA, Hopwood JJ, Snel MF. Trim PJ, et al. Among authors: hopwood jj. Rapid Commun Mass Spectrom. 2014 Apr 30;28(8):933-8. doi: 10.1002/rcm.6861. Rapid Commun Mass Spectrom. 2014. PMID: 24623698

3

Synthesis and mass spectrometric analysis of disaccharides from methanolysis of heparan sulfate.

He QQ, Trim PJ, Snel MF, Hopwood JJ, Ferro V. He QQ, et al. Among authors: hopwood jj. Org Biomol Chem. 2018 Nov 21;16(45):8791-8803. doi: 10.1039/c8ob02225a. Org Biomol Chem. 2018. PMID: 30403218

4

Synthetic Disaccharide Standards Enable Quantitative Analysis of Stored Heparan Sulfate in MPS IIIA Murine Brain Regions.

He QQ, Trim PJ, Lau AA, King BM, Hopwood JJ, Hemsley KM, Snel MF, Ferro V. He QQ, et al. Among authors: hopwood jj. ACS Chem Neurosci. 2019 Aug 21;10(8):3847-3858. doi: 10.1021/acschemneuro.9b00328. Epub 2019 Jul 18. ACS Chem Neurosci. 2019. PMID: 31264853

5

Delivery of therapeutic protein for prevention of neurodegenerative changes: comparison of different CSF-delivery methods.

Marshall NR, Hassiotis S, King B, Rozaklis T, Trim PJ, Duplock SK, Winner LK, Beard H, Snel MF, Jolly RD, Hopwood JJ, Hemsley KM. Marshall NR, et al. Among authors: hopwood jj. Exp Neurol. 2015 Jan;263:79-90. doi: 10.1016/j.expneurol.2014.09.008. Epub 2014 Sep 22. Exp Neurol. 2015. PMID: 25246230

6

Evaluation of enzyme dose and dose-frequency in ameliorating substrate accumulation in MPS IIIA Huntaway dog brain.

King B, Marshall N, Beard H, Hassiotis S, Trim PJ, Snel MF, Rozaklis T, Jolly RD, Hopwood JJ, Hemsley KM. King B, et al. Among authors: hopwood jj. J Inherit Metab Dis. 2015 Mar;38(2):341-50. doi: 10.1007/s10545-014-9790-8. Epub 2014 Nov 25. J Inherit Metab Dis. 2015. PMID: 25421091

7

Determination of the role of injection site on the efficacy of intra-CSF enzyme replacement therapy in MPS IIIA mice.

Beard H, Luck AJ, Hassiotis S, King B, Trim PJ, Snel MF, Hopwood JJ, Hemsley KM. Beard H, et al. Among authors: hopwood jj. Mol Genet Metab. 2015 May;115(1):33-40. doi: 10.1016/j.ymgme.2015.03.002. Epub 2015 Mar 12. Mol Genet Metab. 2015. PMID: 25795516

8

Low-dose, continual enzyme delivery ameliorates some aspects of established brain disease in a mouse model of a childhood-onset neurodegenerative disorder.

King B, Setford ML, Hassiotis S, Trim PJ, Duplock S, Tucker JN, Hattersley K, Snel MF, Hopwood JJ, Hemsley KM. King B, et al. Among authors: hopwood jj. Exp Neurol. 2016 Apr;278:11-21. doi: 10.1016/j.expneurol.2015.11.013. Epub 2015 Nov 26. Exp Neurol. 2016. PMID: 26626972

9

Low-dose, continuous enzyme replacement therapy ameliorates brain pathology in the neurodegenerative lysosomal disorder mucopolysaccharidosis type IIIA.

King B, Hassiotis S, Rozaklis T, Beard H, Trim PJ, Snel MF, Hopwood JJ, Hemsley KM. King B, et al. Among authors: hopwood jj. J Neurochem. 2016 May;137(3):409-22. doi: 10.1111/jnc.13533. Epub 2016 Feb 24. J Neurochem. 2016. PMID: 26762778 Free article.

10

Slow, continuous enzyme replacement via spinal CSF in dogs with the paediatric-onset neurodegenerative disease, MPS IIIA.

King B, Marshall NR, Hassiotis S, Trim PJ, Tucker J, Hattersley K, Snel MF, Jolly RD, Hopwood JJ, Hemsley KM. King B, et al. Among authors: hopwood jj. J Inherit Metab Dis. 2017 May;40(3):443-453. doi: 10.1007/s10545-016-9994-1. Epub 2016 Nov 10. J Inherit Metab Dis. 2017. PMID: 27832416

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