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889 results

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Page 1
Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.
Chiang SH, Harrington WW, Luo G, Milliken NO, Ulrich JC, Chen J, Rajpal DK, Qian Y, Carpenter T, Murray R, Geske RS, Stimpson SA, Kramer HF, Haffner CD, Becherer JD, Preugschat F, Billin AN. Chiang SH, et al. Among authors: carpenter t. PLoS One. 2015 Aug 19;10(8):e0134927. doi: 10.1371/journal.pone.0134927. eCollection 2015. PLoS One. 2015. PMID: 26287487 Free PMC article.
Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.
Becherer JD, Boros EE, Carpenter TY, Cowan DJ, Deaton DN, Haffner CD, Jeune MR, Kaldor IW, Poole JC, Preugschat F, Rheault TR, Schulte CA, Shearer BG, Shearer TW, Shewchuk LM, Smalley TL Jr, Stewart EL, Stuart JD, Ulrich JC. Becherer JD, et al. J Med Chem. 2015 Sep 10;58(17):7021-56. doi: 10.1021/acs.jmedchem.5b00992. Epub 2015 Aug 24. J Med Chem. 2015. PMID: 26267483
Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.
Haffner CD, Becherer JD, Boros EE, Cadilla R, Carpenter T, Cowan D, Deaton DN, Guo Y, Harrington W, Henke BR, Jeune MR, Kaldor I, Milliken N, Petrov KG, Preugschat F, Schulte C, Shearer BG, Shearer T, Smalley TL Jr, Stewart EL, Stuart JD, Ulrich JC. Haffner CD, et al. Among authors: carpenter t. J Med Chem. 2015 Apr 23;58(8):3548-71. doi: 10.1021/jm502009h. Epub 2015 Apr 10. J Med Chem. 2015. PMID: 25828863
Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2.
Haffner CD, Thomson SA, Guo Y, Petrov K, Larkin A, Banker P, Schaaf G, Dickerson S, Gobel J, Gillie D, Condreay JP, Poole C, Carpenter T, Ulrich J. Haffner CD, et al. Among authors: carpenter t. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6989-92. doi: 10.1016/j.bmcl.2010.09.131. Epub 2010 Oct 23. Bioorg Med Chem Lett. 2010. PMID: 20974533
Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).
Deng H, O'Keefe H, Davie CP, Lind KE, Acharya RA, Franklin GJ, Larkin J, Matico R, Neeb M, Thompson MM, Lohr T, Gross JW, Centrella PA, O'Donovan GK, Bedard KL, van Vloten K, Mataruse S, Skinner SR, Belyanskaya SL, Carpenter TY, Shearer TW, Clark MA, Cuozzo JW, Arico-Muendel CC, Morgan BA. Deng H, et al. Among authors: carpenter ty. J Med Chem. 2012 Aug 23;55(16):7061-79. doi: 10.1021/jm300449x. Epub 2012 Aug 14. J Med Chem. 2012. PMID: 22891645
Systematic Review: Efficacy of Medical Therapy on Outcomes Important to Adult Patients with X-Linked Hypophosphatemia.
Ali DS, Mirza RD, Alsarraf F, Hussein S, Abu Alrob H, Appelman-Dijkstra NM, Beck-Nielsen SS, Biosse-Duplan M, Brandi ML, Carpenter TO, Chaussain C, Cohen-Solal M, Crowley RK, Dandurand K, Florenzano P, Fukumoto S, Gagnon C, Goodyer P, Grasemann C, Imel EA, Jan de Beur SM, Lehman A, Lewiecki EM, Morgante E, Ward LM, Khan AA, Guyatt G. Ali DS, et al. Among authors: carpenter to. J Clin Endocrinol Metab. 2024 Dec 23:dgae890. doi: 10.1210/clinem/dgae890. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 39715351
Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections.
Lydon E, Osborne CM, Wagner BD, Ambroggio L, Harris JK, Reeder R, Carpenter TC, Maddux AB, Leroue MK, Yehya N, DeRisi JL, Hall MW, Zuppa AF, Carcillo J, Meert K, Sapru A, Pollack MM, McQuillen P, Notterman DA, Langelier CR, Mourani PM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). Lydon E, et al. Among authors: carpenter tc. mSystems. 2024 Nov 29:e0133524. doi: 10.1128/msystems.01335-24. Online ahead of print. mSystems. 2024. PMID: 39611811 Free article.
Publisher Correction: Resuscitation arterial waveform quantification and outcomes in pediatric bidirectional Glenn and Fontan patients.
Yates AR, Hehir DA, Reeder RW, Berger JT, Fernandez R, Frazier AH, Graham K, McQuillen PS, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Wolfe HA, Berg RA, Sutton RM; ICU-RESUS; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups. Yates AR, et al. Pediatr Res. 2024 Nov 26. doi: 10.1038/s41390-024-03749-5. Online ahead of print. Pediatr Res. 2024. PMID: 39592774 No abstract available.
Protocol for the Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Studies.
Faustino EVS, Kandil SB, Leroue MK, Sochet AA, Kong M, Cholette JM, Nellis ME, Pinto MG, Chegondi M, Ramirez M, Schreiber H, Kerris EWJ, Glau CL, Kolmar A, Muisyo TM, Sharathkumar A, Polikoff L, Silva CT, Ehrlich L, Navarro OM, Spinella PC, Raffini L, Taylor SN, McPartland T, Shabanova V; Catheter-Related Early Thromboprophylaxis with Enoxaparin (CRETE) Studies Investigators and the Pediatric Critical Care Blood Research Network (BloodNet) of the Pediatric Acute Lung Injury and Sepsis Investigators Network (PALISI). Faustino EVS, et al. Pediatr Crit Care Med. 2024 Nov 19. doi: 10.1097/PCC.0000000000003648. Online ahead of print. Pediatr Crit Care Med. 2024. PMID: 39560771
Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections.
Lydon E, Osborne CM, Wagner BD, Ambroggio L, Kirk Harris J, Reeder R, Carpenter TC, Maddux AB, Leroue MK, Yehya N, DeRisi JL, Hall MW, Zuppa AF, Carcillo J, Meert K, Sapru A, Pollack MM, McQuillen P, Notterman DA, Langelier CR, Mourani PM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN). Lydon E, et al. Among authors: carpenter tc. bioRxiv [Preprint]. 2024 Oct 10:2024.10.08.617294. doi: 10.1101/2024.10.08.617294. bioRxiv. 2024. Update in: mSystems. 2024 Nov 29:e0133524. doi: 10.1128/msystems.01335-24 PMID: 39416167 Free PMC article. Updated. Preprint.
889 results