Gonias SL - Search Results

1

Urokinase receptor and resistance to targeted anticancer agents.

Gonias SL, Hu J. Gonias SL, et al. Front Pharmacol. 2015 Jul 27;6:154. doi: 10.3389/fphar.2015.00154. eCollection 2015. Front Pharmacol. 2015. PMID: 26283964 Free PMC article. Review.

2

Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.

Hu J, Jo M, Cavenee WK, Furnari F, VandenBerg SR, Gonias SL. Hu J, et al. Among authors: gonias sl. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15984-9. doi: 10.1073/pnas.1113416108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896743 Free PMC article.

3

Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors.

Staudt ND, Jo M, Hu J, Bristow JM, Pizzo DP, Gaultier A, VandenBerg SR, Gonias SL. Staudt ND, et al. Among authors: gonias sl. Cancer Res. 2013 Jul 1;73(13):3902-12. doi: 10.1158/0008-5472.CAN-12-4233. Epub 2013 Apr 30. Cancer Res. 2013. PMID: 23633492 Free PMC article.

4

uPAR induces expression of transforming growth factor β and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.

Hu J, Jo M, Eastman BM, Gilder AS, Bui JD, Gonias SL. Hu J, et al. Among authors: gonias sl. Am J Pathol. 2014 Dec;184(12):3384-93. doi: 10.1016/j.ajpath.2014.08.003. Epub 2014 Oct 11. Am J Pathol. 2014. PMID: 25310970 Free PMC article.

5

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.

Hu J, Muller KA, Furnari FB, Cavenee WK, VandenBerg SR, Gonias SL. Hu J, et al. Among authors: gonias sl. Oncogene. 2015 Jul 30;34(31):4078-88. doi: 10.1038/onc.2014.336. Epub 2014 Oct 27. Oncogene. 2015. PMID: 25347738 Free PMC article.

6

A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.

Wykosky J, Hu J, Gomez GG, Taylor T, Villa GR, Pizzo D, VandenBerg SR, Thorne AH, Chen CC, Mischel PS, Gonias SL, Cavenee WK, Furnari FB. Wykosky J, et al. Among authors: gonias sl. Cancer Res. 2015 Jan 15;75(2):394-404. doi: 10.1158/0008-5472.CAN-14-2004. Epub 2014 Nov 28. Cancer Res. 2015. PMID: 25432173 Free PMC article.

7

Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion.

Gilder AS, Jones KA, Hu J, Wang L, Chen CC, Carter BS, Gonias SL. Gilder AS, et al. Among authors: gonias sl. J Biol Chem. 2015 Jun 12;290(24):14798-809. doi: 10.1074/jbc.M115.637488. Epub 2015 Apr 2. J Biol Chem. 2015. PMID: 25837250 Free PMC article.

8

mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer.

Hau AM, Leivo MZ, Gilder AS, Hu JJ, Gonias SL, Hansel DE. Hau AM, et al. Among authors: gonias sl. Cell Signal. 2017 Jan;29:96-106. doi: 10.1016/j.cellsig.2016.10.010. Epub 2016 Oct 21. Cell Signal. 2017. PMID: 27777073

9

The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres.

Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL. Gilder AS, et al. Among authors: gonias sl. Sci Rep. 2018 Feb 14;8(1):2982. doi: 10.1038/s41598-018-21358-1. Sci Rep. 2018. PMID: 29445239 Free PMC article.

10

Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator.

Jo M, Thomas KS, Marozkina N, Amin TJ, Silva CM, Parsons SJ, Gonias SL. Jo M, et al. Among authors: gonias sl. J Biol Chem. 2005 Apr 29;280(17):17449-57. doi: 10.1074/jbc.M413141200. Epub 2005 Feb 21. J Biol Chem. 2005. PMID: 15728176 Free article.

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