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UGT2B28 accelerates prostate cancer progression through stabilization of the endocytic adaptor protein HIP1 regulating AR and EGFR pathways.
Lacombe L, Hovington H, Brisson H, Mehdi S, Beillevaire D, Émond JP, Wagner A, Villeneuve L, Simonyan D, Ouellet V, Barrès V, Latour M, Aprikian A, Bergeron A, Castonguay V, Couture F, Chevalier S, Brimo F, Fazli L, Fleshner N, Gleave M, Karakiewicz PI, Lattouf JB, Trudel D, van der Kwast T, Mes-Masson AM, Pouliot F, Fradet Y, Audet-Walsh E, Saad F, Guillemette C, Lévesque E. Lacombe L, et al. Among authors: trudel d. Cancer Lett. 2023 Jan 28;553:215994. doi: 10.1016/j.canlet.2022.215994. Epub 2022 Nov 4. Cancer Lett. 2023. PMID: 36343786
A phase IIb randomized placebo-controlled trial testing the effect of MAG-EPA long-chain omega-3 fatty acid dietary supplement on prostate cancer proliferation.
Robitaille K, Guertin MH, Jamshidi A, Xu HW, Hovington H, Pelletier JF, Beaudoin L, Gevariya N, Lacombe L, Tiguert R, Caumartin Y, Dujardin T, Toren P, Lodde M, Racine É, Trudel D, Perigny M, Duchesne T, Savard J, Julien P, Fradet Y, Fradet V. Robitaille K, et al. Among authors: trudel d. Commun Med (Lond). 2024 Mar 22;4(1):56. doi: 10.1038/s43856-024-00456-4. Commun Med (Lond). 2024. PMID: 38519581 Free PMC article.
Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease.
Koppe L, Nyam E, Vivot K, Manning Fox JE, Dai XQ, Nguyen BN, Trudel D, Attané C, Moullé VS, MacDonald PE, Ghislain J, Poitout V. Koppe L, et al. Among authors: trudel d. J Clin Invest. 2016 Sep 1;126(9):3598-612. doi: 10.1172/JCI86181. Epub 2016 Aug 15. J Clin Invest. 2016. PMID: 27525435 Free PMC article.
Metformin Abrogates Age-Associated Ovarian Fibrosis.
McCloskey CW, Cook DP, Kelly BS, Azzi F, Allen CH, Forsyth A, Upham J, Rayner KJ, Gray DA, Boyd RW, Murugkar S, Lo B, Trudel D, Senterman MK, Vanderhyden BC. McCloskey CW, et al. Among authors: trudel d. Clin Cancer Res. 2020 Feb 1;26(3):632-642. doi: 10.1158/1078-0432.CCR-19-0603. Epub 2019 Oct 9. Clin Cancer Res. 2020. PMID: 31597663
94 results