Mercola M - Search Results

1

1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells.

Okolotowicz KJ, Bushway P, Lanier M, Gilley C, Mercola M, Cashman JR. Okolotowicz KJ, et al. Among authors: mercola m. Bioorg Med Chem. 2015 Sep 1;23(17):5282-92. doi: 10.1016/j.bmc.2015.07.073. Epub 2015 Aug 4. Bioorg Med Chem. 2015. PMID: 26278027 Free PMC article.

2

Natural and synthetic regulators of embryonic stem cell cardiogenesis.

Willems E, Bushway PJ, Mercola M. Willems E, et al. Among authors: mercola m. Pediatr Cardiol. 2009 Jul;30(5):635-42. doi: 10.1007/s00246-009-9409-2. Epub 2009 Mar 25. Pediatr Cardiol. 2009. PMID: 19319460 Free PMC article.

3

Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm.

Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J, Mercola M. Willems E, et al. Among authors: mercola m. Circ Res. 2011 Aug 5;109(4):360-4. doi: 10.1161/CIRCRESAHA.111.249540. Epub 2011 Jul 7. Circ Res. 2011. PMID: 21737789 Free PMC article.

4

Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure-activity relationship study based on inhibitors for the Wnt response.

Lanier M, Schade D, Willems E, Tsuda M, Spiering S, Kalisiak J, Mercola M, Cashman JR. Lanier M, et al. Among authors: mercola m. J Med Chem. 2012 Jan 26;55(2):697-708. doi: 10.1021/jm2010223. Epub 2012 Jan 13. J Med Chem. 2012. PMID: 22191557 Free PMC article.

5

Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells.

Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. Willems E, et al. Among authors: mercola m. Cell Stem Cell. 2012 Aug 3;11(2):242-52. doi: 10.1016/j.stem.2012.04.025. Cell Stem Cell. 2012. PMID: 22862949 Free PMC article.

6

Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling.

Schade D, Lanier M, Willems E, Okolotowicz K, Bushway P, Wahlquist C, Gilley C, Mercola M, Cashman JR. Schade D, et al. Among authors: mercola m. J Med Chem. 2012 Nov 26;55(22):9946-57. doi: 10.1021/jm301144g. Epub 2012 Nov 6. J Med Chem. 2012. PMID: 23130626 Free PMC article.

7

High content screening for modulators of cardiac differentiation in human pluripotent stem cells.

Spiering S, Davidovics H, Bushway PJ, Mercola M, Willems E. Spiering S, et al. Among authors: mercola m. Methods Mol Biol. 2015;1263:43-61. doi: 10.1007/978-1-4939-2269-7_4. Methods Mol Biol. 2015. PMID: 25618335 Free PMC article.

8

Novel tertiary sulfonamides as potent anti-cancer agents.

Okolotowicz KJ, Dwyer M, Ryan D, Cheng J, Cashman EA, Moore S, Mercola M, Cashman JR. Okolotowicz KJ, et al. Among authors: mercola m. Bioorg Med Chem. 2018 Aug 15;26(15):4441-4451. doi: 10.1016/j.bmc.2018.07.042. Epub 2018 Jul 25. Bioorg Med Chem. 2018. PMID: 30075999

9

b-Annulated 1,4-dihydropyridines as Notch inhibitors.

Gómez-Galeno JE, Hurtado C, Cheng J, Yardimci C, Mercola M, Cashman JR. Gómez-Galeno JE, et al. Among authors: mercola m. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3363-3367. doi: 10.1016/j.bmcl.2018.09.002. Epub 2018 Sep 5. Bioorg Med Chem Lett. 2018. PMID: 30201292 Free PMC article.

10

Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes.

Cashman JR, Ryan D, McKeithan WL, Okolotowicz K, Gomez-Galeno J, Johnson M, Sampson KJ, Kass RS, Pezhouman A, Karagueuzian HS, Mercola M. Cashman JR, et al. Among authors: mercola m. J Med Chem. 2021 May 13;64(9):5384-5403. doi: 10.1021/acs.jmedchem.0c01545. Epub 2021 May 4. J Med Chem. 2021. PMID: 33942619

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