Brandt M - Search Results

1

Interaction between rat prostatic steroid 5 alpha-reductase and 3-carboxy-17 beta-substituted steroids: novel mechanism of enzyme inhibition.

Levy MA, Brandt M, Holt DA, Metcalf BW. Levy MA, et al. Among authors: brandt m. J Steroid Biochem. 1989;34(1-6):571-5. doi: 10.1016/0022-4731(89)90148-9. J Steroid Biochem. 1989. PMID: 2626051

2

Mechanistic studies with solubilized rat liver steroid 5 alpha-reductase: elucidation of the kinetic mechanism.

Levy MA, Brandt M, Greway AT. Levy MA, et al. Among authors: brandt m. Biochemistry. 1990 Mar 20;29(11):2808-15. doi: 10.1021/bi00463a025. Biochemistry. 1990. PMID: 2140700

3

Studies on the mechanism of steroid 5 alpha-reductase inhibition by 3-carboxy A-ring aryl steroids.

Brandt M, Greway AT, Holt DA, Metcalf BW, Levy MA. Brandt M, et al. J Steroid Biochem Mol Biol. 1990 Nov 30;37(4):575-9. doi: 10.1016/0960-0760(90)90403-8. J Steroid Biochem Mol Biol. 1990. PMID: 2278842

4

Steroidal A ring aryl carboxylic acids: a new class of steroid 5 alpha-reductase inhibitors.

Holt DA, Levy MA, Ladd DL, Oh HJ, Erb JM, Heaslip JI, Brandt M, Metcalf BW. Holt DA, et al. Among authors: brandt m. J Med Chem. 1990 Mar;33(3):937-42. doi: 10.1021/jm00165a009. J Med Chem. 1990. PMID: 2308144

5

Inhibition of steroid 5 alpha-reductase by unsaturated 3-carboxysteroids.

Holt DA, Levy MA, Oh HJ, Erb JM, Heaslip JI, Brandt M, Lan-Hargest HY, Metcalf BW. Holt DA, et al. Among authors: brandt m. J Med Chem. 1990 Mar;33(3):943-50. doi: 10.1021/jm00165a010. J Med Chem. 1990. PMID: 2308145

6

Inhibition of rat liver steroid 5 alpha-reductase by 3-androstene-3-carboxylic acids: mechanism of enzyme-inhibitor interaction.

Levy MA, Brandt M, Heys JR, Holt DA, Metcalf BW. Levy MA, et al. Among authors: brandt m. Biochemistry. 1990 Mar 20;29(11):2815-24. doi: 10.1021/bi00463a026. Biochemistry. 1990. PMID: 2346747

7

3 Beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase from bovine adrenals: mechanism of inhibition by 3-oxo-4-aza steroids and kinetic mechanism of the dehydrogenase.

Brandt M, Levy MA. Brandt M, et al. Biochemistry. 1989 Jan 10;28(1):140-8. doi: 10.1021/bi00427a021. Biochemistry. 1989. PMID: 2706240

8

Inhibition of 3(17)beta-hydroxysteroid dehydrogenase from Pseudomonas testosteroni by steroidal A ring fused pyrazoles.

Levy MA, Holt DA, Brandt M, Metcalf BW. Levy MA, et al. Among authors: brandt m. Biochemistry. 1987 Apr 21;26(8):2270-9. doi: 10.1021/bi00382a030. Biochemistry. 1987. PMID: 3040087

9

Inhibition of pyridine-nucleotide-dependent enzymes by pyrazoles. Synthesis and enzymology of a novel A-ring pyrazole steroid.

Holt DA, Levy MA, Brandt M, Metcalf BW. Holt DA, et al. Among authors: brandt m. Steroids. 1986 Sep-Oct;48(3-4):213-22. doi: 10.1016/0039-128x(86)90004-8. Steroids. 1986. PMID: 3481887

10

Cloning, expression and functional characterization of type 1 and type 2 steroid 5 alpha-reductases from Cynomolgus monkey: comparisons with human and rat isoenzymes.

Levy MA, Brandt M, Sheedy KM, Holt DA, Heaslip JI, Trill JJ, Ryan PJ, Morris RA, Garrison LM, Bergsma DJ. Levy MA, et al. Among authors: brandt m. J Steroid Biochem Mol Biol. 1995 Apr;52(4):307-19. doi: 10.1016/0960-0760(94)00183-m. J Steroid Biochem Mol Biol. 1995. PMID: 7734398

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