Harmston N - Search Results

1

Wnt addiction of genetically defined cancers reversed by PORCN inhibition.

Madan B, Ke Z, Harmston N, Ho SY, Frois AO, Alam J, Jeyaraj DA, Pendharkar V, Ghosh K, Virshup IH, Manoharan V, Ong EH, Sangthongpitag K, Hill J, Petretto E, Keller TH, Lee MA, Matter A, Virshup DM. Madan B, et al. Among authors: harmston n. Oncogene. 2016 Apr 28;35(17):2197-207. doi: 10.1038/onc.2015.280. Epub 2015 Aug 10. Oncogene. 2016. PMID: 26257057 Free PMC article.

2

Wnt proteins synergize to activate β-catenin signaling.

Alok A, Lei Z, Jagannathan NS, Kaur S, Harmston N, Rozen SG, Tucker-Kellogg L, Virshup DM. Alok A, et al. Among authors: harmston n. J Cell Sci. 2017 May 1;130(9):1532-1544. doi: 10.1242/jcs.198093. Epub 2017 Mar 13. J Cell Sci. 2017. PMID: 28289266

3

An embryonic system to assess direct and indirect Wnt transcriptional targets.

Suresh J, Harmston N, Lim KK, Kaur P, Jin HJ, Lusk JB, Petretto E, Tolwinski NS. Suresh J, et al. Among authors: harmston n. Sci Rep. 2017 Sep 11;7(1):11092. doi: 10.1038/s41598-017-11519-z. Sci Rep. 2017. PMID: 28894169 Free PMC article.

4

Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis.

Madan B, Harmston N, Nallan G, Montoya A, Faull P, Petretto E, Virshup DM. Madan B, et al. Among authors: harmston n. J Clin Invest. 2018 Dec 3;128(12):5620-5633. doi: 10.1172/JCI122383. Epub 2018 Nov 12. J Clin Invest. 2018. PMID: 30300142 Free PMC article.

5

Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture.

Tjin MS, Chua AWC, Moreno-Moral A, Chong LY, Tang PY, Harmston NP, Cai Z, Petretto E, Tan BK, Tryggvason K. Tjin MS, et al. Nat Commun. 2018 Oct 30;9(1):4432. doi: 10.1038/s41467-018-06934-3. Nat Commun. 2018. PMID: 30377295 Free PMC article.

6

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors.

Yap L, Wang JW, Moreno-Moral A, Chong LY, Sun Y, Harmston N, Wang X, Chong SY, Vanezis K, Öhman MK, Wei H, Bunte R, Gosh S, Cook S, Hovatta O, de Kleijn DPV, Petretto E, Tryggvason K. Yap L, et al. Among authors: harmston n. Cell Rep. 2019 Mar 19;26(12):3231-3245.e9. doi: 10.1016/j.celrep.2019.02.083. Cell Rep. 2019. PMID: 30893597 Free article.

7

Broad regulation of gene isoform expression by Wnt signaling in cancer.

Idris M, Harmston N, Petretto E, Madan B, Virshup DM. Idris M, et al. Among authors: harmston n. RNA. 2019 Dec;25(12):1696-1713. doi: 10.1261/rna.071506.119. Epub 2019 Sep 10. RNA. 2019. PMID: 31506381 Free PMC article.

8

The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.

Yu J, Yusoff PAM, Woutersen DTJ, Goh P, Harmston N, Smits R, Epstein DM, Virshup DM, Madan B. Yu J, et al. Among authors: harmston n. Cancer Res. 2020 Dec 15;80(24):5619-5632. doi: 10.1158/0008-5472.CAN-20-0957. Epub 2020 Oct 16. Cancer Res. 2020. PMID: 33067269

9

Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation.

Liu S, Harmston N, Glaser TL, Wong Y, Zhong Z, Madan B, Virshup DM, Petretto E. Liu S, et al. Among authors: harmston n. Genome Med. 2020 Oct 22;12(1):89. doi: 10.1186/s13073-020-00788-5. Genome Med. 2020. PMID: 33092630 Free PMC article.

10

Widespread Repression of Gene Expression in Cancer by a Wnt/β-Catenin/MAPK Pathway.

Harmston N, Lim JYS, Arqués O, Palmer HG, Petretto E, Virshup DM, Madan B. Harmston N, et al. Cancer Res. 2021 Jan 15;81(2):464-475. doi: 10.1158/0008-5472.CAN-20-2129. Epub 2020 Nov 17. Cancer Res. 2021. PMID: 33203702

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