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Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.
Satoh T, McKercher SR, Lipton SA. Satoh T, et al. Among authors: mckercher sr. Free Radic Biol Med. 2013 Dec;65:645-657. doi: 10.1016/j.freeradbiomed.2013.07.022. Epub 2013 Jul 25. Free Radic Biol Med. 2013. PMID: 23892355 Free PMC article. Review.
Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes.
Satoh T, Rezaie T, Seki M, Sunico CR, Tabuchi T, Kitagawa T, Yanagitai M, Senzaki M, Kosegawa C, Taira H, McKercher SR, Hoffman JK, Roth GP, Lipton SA. Satoh T, et al. Among authors: mckercher sr. J Neurochem. 2011 Nov;119(3):569-78. doi: 10.1111/j.1471-4159.2011.07449.x. Epub 2011 Sep 21. J Neurochem. 2011. PMID: 21883218 Free PMC article.
MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.
Nagar S, Noveral SM, Trudler D, Lopez KM, McKercher SR, Han X, Yates JR 3rd, Piña-Crespo JC, Nakanishi N, Satoh T, Okamoto SI, Lipton SA. Nagar S, et al. Among authors: mckercher sr. Proc Natl Acad Sci U S A. 2017 May 16;114(20):E4048-E4056. doi: 10.1073/pnas.1613067114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461502 Free PMC article.
Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in synaptosomes of HIV/gp120 transgenic mice: implications for HIV-associated neurodegeneration.
Banerjee S, Liao L, Russo R, Nakamura T, McKercher SR, Okamoto S, Haun F, Nikzad R, Zaidi R, Holland E, Eroshkin A, Yates JR 3rd, Lipton SA. Banerjee S, et al. Among authors: mckercher sr. Exp Neurol. 2012 Aug;236(2):298-306. doi: 10.1016/j.expneurol.2012.04.013. Epub 2012 May 1. Exp Neurol. 2012. PMID: 22575597 Free PMC article.
Protective effect of carnosic acid, a pro-electrophilic compound, in models of oxidative stress and light-induced retinal degeneration.
Rezaie T, McKercher SR, Kosaka K, Seki M, Wheeler L, Viswanath V, Chun T, Joshi R, Valencia M, Sasaki S, Tozawa T, Satoh T, Lipton SA. Rezaie T, et al. Among authors: mckercher sr. Invest Ophthalmol Vis Sci. 2012 Nov 27;53(12):7847-54. doi: 10.1167/iovs.12-10793. Invest Ophthalmol Vis Sci. 2012. PMID: 23081978 Free PMC article.
78 results