Hazra AB - Search Results

1

Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.

Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP. Mehta AP, et al. Among authors: hazra ab. J Am Chem Soc. 2015 Aug 26;137(33):10444-7. doi: 10.1021/jacs.5b03576. Epub 2015 Aug 13. J Am Chem Soc. 2015. PMID: 26237670 Free PMC article.

2

Cofactor biosynthesis--still yielding fascinating new biological chemistry.

Begley TP, Chatterjee A, Hanes JW, Hazra A, Ealick SE. Begley TP, et al. Curr Opin Chem Biol. 2008 Apr;12(2):118-25. doi: 10.1016/j.cbpa.2008.02.006. Epub 2008 Apr 2. Curr Opin Chem Biol. 2008. PMID: 18314013 Free PMC article. Review.

3

Biosynthesis of the thiamin thiazole in Bacillus subtilis: identification of the product of the thiazole synthase-catalyzed reaction.

Hazra A, Chatterjee A, Begley TP. Hazra A, et al. J Am Chem Soc. 2009 Mar 11;131(9):3225-9. doi: 10.1021/ja806752h. J Am Chem Soc. 2009. PMID: 19216519 Free PMC article.

4

A "radical dance" in thiamin biosynthesis: mechanistic analysis of the bacterial hydroxymethylpyrimidine phosphate synthase.

Chatterjee A, Hazra AB, Abdelwahed S, Hilmey DG, Begley TP. Chatterjee A, et al. Among authors: hazra ab. Angew Chem Int Ed Engl. 2010 Nov 8;49(46):8653-6. doi: 10.1002/anie.201003419. Angew Chem Int Ed Engl. 2010. PMID: 20886485 Free PMC article. No abstract available.

5

A missing enzyme in thiamin thiazole biosynthesis: identification of TenI as a thiazole tautomerase.

Hazra AB, Han Y, Chatterjee A, Zhang Y, Lai RY, Ealick SE, Begley TP. Hazra AB, et al. J Am Chem Soc. 2011 Jun 22;133(24):9311-9. doi: 10.1021/ja1110514. Epub 2011 May 26. J Am Chem Soc. 2011. PMID: 21534620 Free PMC article.

6

Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.

Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP. Lai RY, et al. J Am Chem Soc. 2012 Jun 6;134(22):9157-9. doi: 10.1021/ja302474a. Epub 2012 May 24. J Am Chem Soc. 2012. PMID: 22568620 Free PMC article.

7

Analysis of substrate specificity in CobT homologs reveals widespread preference for DMB, the lower axial ligand of vitamin B(12).

Hazra AB, Tran JL, Crofts TS, Taga ME. Hazra AB, et al. Chem Biol. 2013 Oct 24;20(10):1275-85. doi: 10.1016/j.chembiol.2013.08.007. Epub 2013 Sep 19. Chem Biol. 2013. PMID: 24055005

8

Cobamide structure depends on both lower ligand availability and CobT substrate specificity.

Crofts TS, Seth EC, Hazra AB, Taga ME. Crofts TS, et al. Among authors: hazra ab. Chem Biol. 2013 Oct 24;20(10):1265-74. doi: 10.1016/j.chembiol.2013.08.006. Epub 2013 Sep 19. Chem Biol. 2013. PMID: 24055007

9

Regiospecific formation of cobamide isomers is directed by CobT.

Crofts TS, Hazra AB, Tran JL, Sokolovskaya OM, Osadchiy V, Ad O, Pelton J, Bauer S, Taga ME. Crofts TS, et al. Among authors: hazra ab. Biochemistry. 2014 Dec 16;53(49):7805-15. doi: 10.1021/bi501147d. Epub 2014 Dec 5. Biochemistry. 2014. PMID: 25412146

10

Anaerobic biosynthesis of the lower ligand of vitamin B12.

Hazra AB, Han AW, Mehta AP, Mok KC, Osadchiy V, Begley TP, Taga ME. Hazra AB, et al. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10792-7. doi: 10.1073/pnas.1509132112. Epub 2015 Aug 5. Proc Natl Acad Sci U S A. 2015. PMID: 26246619 Free PMC article.

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