Al-Ali H - Search Results

1

Phenotypic assays to identify agents that induce reactive gliosis: a counter-screen to prioritize compounds for preclinical animal studies.

Beckerman SR, Jimenez JE, Shi Y, Al-Ali H, Bixby JL, Lemmon VP. Beckerman SR, et al. Assay Drug Dev Technol. 2015 Sep;13(7):377-88. doi: 10.1089/adt.2015.654. Epub 2015 Jul 31. Assay Drug Dev Technol. 2015. PMID: 26230074 Free PMC article.

2

Chemical interrogation of the neuronal kinome using a primary cell-based screening assay.

Al-Ali H, Schürer SC, Lemmon VP, Bixby JL. Al-Ali H, et al. ACS Chem Biol. 2013 May 17;8(5):1027-36. doi: 10.1021/cb300584e. Epub 2013 Mar 19. ACS Chem Biol. 2013. PMID: 23480631 Free PMC article.

3

Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth.

Al-Ali H, Lee DH, Danzi MC, Nassif H, Gautam P, Wennerberg K, Zuercher B, Drewry DH, Lee JK, Lemmon VP, Bixby JL. Al-Ali H, et al. ACS Chem Biol. 2015 Aug 21;10(8):1939-51. doi: 10.1021/acschembio.5b00289. Epub 2015 Jun 24. ACS Chem Biol. 2015. PMID: 26056718 Free PMC article.

4

In vitro models of axon regeneration.

Al-Ali H, Beckerman SR, Bixby JL, Lemmon VP. Al-Ali H, et al. Exp Neurol. 2017 Jan;287(Pt 3):423-434. doi: 10.1016/j.expneurol.2016.01.020. Epub 2016 Jan 27. Exp Neurol. 2017. PMID: 26826447 Free PMC article. Review.

5

Exploiting kinase polypharmacology for nerve regeneration.

Al-Ali H, Bixby JL, Lemmon VP. Al-Ali H, et al. Neural Regen Res. 2016 Jan;11(1):71-2. doi: 10.4103/1673-5374.169614. Neural Regen Res. 2016. PMID: 26981084 Free PMC article. No abstract available.

6

RegenBase: a knowledge base of spinal cord injury biology for translational research.

Callahan A, Abeyruwan SW, Al-Ali H, Sakurai K, Ferguson AR, Popovich PG, Shah NH, Visser U, Bixby JL, Lemmon VP. Callahan A, et al. Database (Oxford). 2016 Apr 7;2016:baw040. doi: 10.1093/database/baw040. Print 2016. Database (Oxford). 2016. PMID: 27055827 Free PMC article.

7

Phenotypic Screening of Small-Molecule Inhibitors: Implications for Therapeutic Discovery and Drug Target Development in Traumatic Brain Injury.

Al-Ali H, Lemmon VP, Bixby JL. Al-Ali H, et al. Methods Mol Biol. 2016;1462:677-88. doi: 10.1007/978-1-4939-3816-2_37. Methods Mol Biol. 2016. PMID: 27604745

8

The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.

Al-Ali H, Ding Y, Slepak T, Wu W, Sun Y, Martinez Y, Xu XM, Lemmon VP, Bixby JL. Al-Ali H, et al. J Neurosci. 2017 Jul 26;37(30):7079-7095. doi: 10.1523/JNEUROSCI.0931-17.2017. Epub 2017 Jun 16. J Neurosci. 2017. PMID: 28626016 Free PMC article.

9

High content analysis of phagocytic activity and cell morphology with PuntoMorph.

Al-Ali H, Gao H, Dalby-Hansen C, Peters VA, Shi Y, Brambilla R. Al-Ali H, et al. J Neurosci Methods. 2017 Nov 1;291:43-50. doi: 10.1016/j.jneumeth.2017.08.004. Epub 2017 Aug 5. J Neurosci Methods. 2017. PMID: 28789994 Free PMC article.

10

Scaffold Ranking and Positional Scanning Identify Novel Neurite Outgrowth Promoters with Nanomolar Potency.

Al-Ali H, Debevec G, Santos RG, Houghten RA, Davis JC, Nefzi A, Lemmon VP, Bixby JL, Giulianotti MA. Al-Ali H, et al. ACS Med Chem Lett. 2018 Sep 24;9(10):1057-1062. doi: 10.1021/acsmedchemlett.8b00425. eCollection 2018 Oct 11. ACS Med Chem Lett. 2018. PMID: 30344917 Free PMC article.

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