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A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02).
Hiruy H, Fuchs EJ, Marzinke MA, Bakshi RP, Breakey JC, Aung WS, Manohar M, Yue C, Caffo BS, Du Y, Abebe KZ, Spiegel HM, Rohan LC, McGowan I, Hendrix CW. Hiruy H, et al. Among authors: rohan lc. AIDS Res Hum Retroviruses. 2015 Nov;31(11):1098-108. doi: 10.1089/AID.2015.0098. Epub 2015 Aug 24. AIDS Res Hum Retroviruses. 2015. PMID: 26227279 Free PMC article. Clinical Trial.
Reformulated tenofovir gel for use as a dual compartment microbicide.
Dezzutti CS, Rohan LC, Wang L, Uranker K, Shetler C, Cost M, Lynam JD, Friend D. Dezzutti CS, et al. Among authors: rohan lc. J Antimicrob Chemother. 2012 Sep;67(9):2139-42. doi: 10.1093/jac/dks173. Epub 2012 May 11. J Antimicrob Chemother. 2012. PMID: 22581908 Free PMC article.
Pharmacokinetics and pharmacodynamics in HIV prevention; current status and future directions: a summary of the DAIDS and BMGF sponsored think tank on pharmacokinetics (PK)/pharmacodynamics (PD) in HIV prevention.
Romano J, Kashuba A, Becker S, Cummins J, Turpin J, Veronese F; Antiretroviral Pharmacology In HIV Prevention Think Tank Participants. Romano J, et al. AIDS Res Hum Retroviruses. 2013 Nov;29(11):1418-27. doi: 10.1089/aid.2013.0122. Epub 2013 May 22. AIDS Res Hum Retroviruses. 2013. PMID: 23614610 Free PMC article. Review.
Rectal pre-exposure prophylaxis (PrEP).
Rohan LC, Yang H, Wang L. Rohan LC, et al. Antiviral Res. 2013 Dec;100 Suppl(0):S17-24. doi: 10.1016/j.antiviral.2013.09.023. Epub 2013 Nov 1. Antiviral Res. 2013. PMID: 24188705 Free PMC article. Review.
127 results